Bernasconi P, Massera E
Drugs Exp Clin Res. 1985;11(10):739-43.
In 39 outpatients suffering from a seasonal epidemic influenza, the antipyretic, analgesic and anti-inflammatory activity of nimesulide granules was compared with that of aspirin + vitamin C granules. The drugs were administered b.i.d., dispensed in one-dose sachets containing either 100 mg of nimesulide or 500 mg aspirin + 300 mg vitamin C. The efficacy of the two treatments was comparable: both drugs brought about a rapid complete recovery in all treated patients. However, nimesulide was better tolerated: only one case of slight gastralgia was recorded in the nimesulide group vs the six cases of side-effects complained of in the aspirin + vitamin C group.
在39例季节性流行性感冒门诊患者中，比较了尼美舒利颗粒与阿司匹林+维生素C颗粒的解热、镇痛和抗炎活性。药物每日给药两次，以单剂量小袋包装，每袋含100毫克尼美舒利或500毫克阿司匹林+300毫克维生素C。两种治疗方法的疗效相当：两种药物均使所有接受治疗的患者迅速完全康复。然而，尼美舒利的耐受性更好：尼美舒利组仅记录到1例轻度胃痛，而阿司匹林+维生素C组有6例患者抱怨出现副作用。
