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越南社区获得性肺炎的接种疫苗儿童中不可分型流感嗜血杆菌和溶血嗜血杆菌的高流行率

High Prevalence of Non-typeable Haemophilus influenzae and Haemophilus haemolyticus Among Vaccinated Children with Community-Acquired Pneumonia in Vietnam.

作者信息

Tran Xuan Duong, Hoang Van Thuan, Dao Thi Loi, Marty Pierre, Gautret Philippe

机构信息

Thai Binh University of Medicine and Pharmacy, Thai Binh, Vietnam.

IHU-Méditerranée Infection, Marseille, France.

出版信息

J Epidemiol Glob Health. 2024 Jun;14(2):498-501. doi: 10.1007/s44197-024-00195-8. Epub 2024 Feb 19.

Abstract

Among 467 children under five hospitalized with community-acquired pneumonia, the prevalence of Haemophilus influenzae or Haemophilus haemolyticus was 60.8%, all cases were non-typable H. influenzae (NTHi) or H. haemolyticus. NTHi/H. haemolyticus PCR detection was associated with about twice the risk for severe disease. The results highlight the need for increased awareness and research efforts to investigate the role of NTHi/H. haemolyticus in severe CAP among children.

摘要

在467名因社区获得性肺炎住院的五岁以下儿童中,流感嗜血杆菌或溶血嗜血杆菌的患病率为60.8%,所有病例均为不可分型流感嗜血杆菌(NTHi)或溶血嗜血杆菌。NTHi/溶血嗜血杆菌PCR检测与严重疾病风险增加约两倍相关。这些结果凸显了提高认识和加大研究力度以调查NTHi/溶血嗜血杆菌在儿童重症社区获得性肺炎中作用的必要性。

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