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骨质疏松症与全髋关节置换术中的骨水泥使用。

Osteoporosis and cement usage in total hip arthroplasty.

机构信息

Weill Cornell Medical College, 1300 York Ave., New York, NY, USA.

Department of Orthopedic Surgery, Hospital for Special Surgery, 535 E 70 St, New York, NY, USA.

出版信息

Eur J Orthop Surg Traumatol. 2024 Apr;34(3):1649-1655. doi: 10.1007/s00590-024-03855-4. Epub 2024 Feb 19.

Abstract

PURPOSE

Cement usage in total hip arthroplasty (THA) is increasingly common. However, osteoporosis-related fracture risk in cemented vs uncemented THA patients is poorly characterized. We aim to analyze the usage of metabolic bone care and osteoporosis fracture risk in cemented vs uncemented THA patients using FRAX and radiographic bone measurements.

METHODS

Chart review on 250 THA patients was performed retrospectively. Demographics, FRAX scores, hip radiograph measurements, osteoporosis diagnosis, treatment and screening were compared between cemented and uncemented THA patients. Logistic regression model was used to analyze factors influencing cement usage.

RESULTS

Cemented THA patients have significantly higher osteoporosis-related fracture risk as measured by FRAX major (20% vs 13%) and FRAX hip (8% vs 5%). There is no significant difference in osteoporosis treatment, vitamin D / calcium supplementation, or metabolic bone disease screening based on patients' cement status. Female sex and rheumatoid arthritis status significantly predict cement usage, but FRAX scores do not predict cement usage. Additionally, 50% (10/20) of patients with Dorr C classification were uncemented.

CONCLUSION

Although some patients undergoing THA with high osteoporosis-related fracture risk were identified and cemented, some risk factors including poor proximal femur shape (by Dorr classification) and poor bone quality (as measured by FRAX score) were potentially overlooked. Cemented patients had an increased risk for fractures but did not receive appropriately increased osteoporosis screening or treatment.

LEVEL OF EVIDENCE

III.

摘要

目的

全髋关节置换术(THA)中使用骨水泥越来越普遍。然而,骨水泥固定与非骨水泥固定 THA 患者的骨质疏松性骨折风险特征尚不明确。我们旨在通过 FRAX 和 X 线骨测量分析骨水泥固定与非骨水泥固定 THA 患者中代谢性骨病的管理和骨质疏松性骨折风险。

方法

回顾性分析了 250 例 THA 患者的病历。比较了骨水泥固定与非骨水泥固定 THA 患者的人口统计学资料、FRAX 评分、髋关节 X 线测量值、骨质疏松症诊断、治疗和筛查情况。采用逻辑回归模型分析影响骨水泥使用的因素。

结果

FRAX 主要(20% vs 13%)和 FRAX 髋部(8% vs 5%)评估,骨水泥固定 THA 患者的骨质疏松性骨折风险显著更高。根据患者的骨水泥状态,骨质疏松症治疗、维生素 D/钙补充剂或代谢性骨病筛查无显著差异。女性和类风湿关节炎状态显著预测骨水泥使用,但 FRAX 评分不能预测骨水泥使用。此外,50%(10/20)Dorr C 型分类的患者未使用骨水泥。

结论

尽管一些接受 THA 治疗且具有较高骨质疏松性骨折风险的患者被识别并进行了骨水泥固定,但一些潜在的危险因素(包括股骨近端形态不佳(Dorr 分类)和骨质量差(FRAX 评分评估))可能被忽视。骨水泥固定患者的骨折风险增加,但并未接受适当增加的骨质疏松症筛查或治疗。

证据等级

III。

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