Ahmad Syed A, Popli Deepika B, Sircar Keya, Hasan Shamimul
Oral and Maxillofacial Surgery, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, IND.
Oral and Maxillofacial Pathology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, IND.
Cureus. 2024 Jan 19;16(1):e52599. doi: 10.7759/cureus.52599. eCollection 2024 Jan.
Basal cell adenoma (BCA) is a rare, benign tumor originating from the epithelial cells of the salivary glands. It was earlier categorized as a subtype of monomorphic adenoma with distinctive histopathological features. BCA usually manifests as asymptomatic, slow-growing masses that exhibit a site and age predilection, commonly affecting the major salivary glands of elderly female patients. Histologically, solid, trabecular, tubular, and membranous patterns are recognized. It is imperative to establish a precise distinction between BCA, pleomorphic adenoma, and malignant salivary gland tumors before initiating treatment to ensure effective management. The standard treatment approach is surgical resection of the tumor. Recurrence and malignant transformation rarely occur, except for the membranous subtype. This article aims to report an unusual case of BCA arising from a minor salivary gland in the upper lip. The post-operative course was unremarkable, with complete healing of the surgical site. No recurrence was observed during a one-year follow-up. BCA arising from a minor salivary gland in the upper lip is an extremely uncommon entity. A comprehensive review of BCA in the upper lip, reported from 1991 to December 2023, revealed only 14 cases.
基底细胞腺瘤(BCA)是一种罕见的良性肿瘤,起源于唾液腺上皮细胞。它曾被归类为具有独特组织病理学特征的单形性腺瘤的一个亚型。BCA通常表现为无症状、生长缓慢的肿块,具有部位和年龄偏好,常见于老年女性患者的大唾液腺。在组织学上,可识别出实性、小梁状、管状和膜状模式。在开始治疗之前,必须在BCA、多形性腺瘤和唾液腺恶性肿瘤之间进行精确区分,以确保有效管理。标准的治疗方法是手术切除肿瘤。除膜状亚型外,复发和恶性转化很少发生。本文旨在报告一例罕见的发生于上唇小唾液腺的BCA病例。术后过程顺利,手术部位完全愈合。在一年的随访中未观察到复发。发生于上唇小唾液腺的BCA是一种极其罕见的情况。对1991年至2023年12月报道的上唇BCA进行的全面综述显示,仅有14例病例。