Piruna Martins Santos Aline, Antônio Lima Dos Santos Marcos, Barbara Abreu Barros Francisco, Gimenez Thais, Gusmão Paraíso Cavalcanti Marcelo
Department of Stomatology, University of São Paulo (USP), School of Dentistry, São Paulo, Brazil.
Department of Dentistry, Metropolitan University of Santos, São Paulo, Brazil.
Saudi Dent J. 2024 Jan;36(1):20-27. doi: 10.1016/j.sdentj.2023.10.010. Epub 2023 Oct 13.
Focal osteoporotic bone marrow defect (FOBMD) is a rare and poorly documented pathology corresponding to an unusual hematopoietic tissue in maxillary bones. Several studies have investigated FOBMD but reported different and heterogenous approaches to a correct diagnosis. Therefore, this systematic review evaluated the relevance of imaging exams in aiding FOBMD diagnosis and the implications in surgical planning for dental implants.The research question was: What is the relevance of imaging tests in aiding FOBMD diagnosis?
Online databases were searched to select articles based on eligibility criteria. The studies included in the systematic review were submitted to bias and applicability assessments using the Joanna Briggs Institute tool for study quality assessment.
A total of 383 articles were obtained from all the databases, 27 studies were included, and all performed biopsies to confirm the diagnosis. The selected studies evaluated 698 patients, including approximately 80% of women, corroborating the literature that notes a higher prevalence of this lesion in women. The reviewed articles showed a low risk of bias for case series, moderate for case reports, and low for cross-sectional studies.
The studies considered in this systematic review have shown that radiographic characteristics may sufficiently identify the lesion and provide a periodic radiographic follow-up. However, it is worth noting the need for CBCT for planning oral rehabilitation through implants to minimize the risks of such complications.
局灶性骨质疏松性骨髓缺损（FOBMD）是一种罕见且文献记载较少的病理情况，对应上颌骨中异常的造血组织。多项研究对FOBMD进行了调查，但报告了不同且异质性的正确诊断方法。因此，本系统评价评估了影像学检查在辅助FOBMD诊断中的相关性以及对牙种植手术规划的影响。研究问题为：影像学检查在辅助FOBMD诊断中的相关性如何？
检索在线数据库，根据纳入标准选择文章。纳入系统评价的研究使用乔安娜·布里格斯研究所研究质量评估工具进行偏倚和适用性评估。
从所有数据库共获得383篇文章，纳入27项研究，所有研究均进行了活检以确诊。所选研究评估了698例患者，其中约80%为女性，这与文献中指出该病变在女性中患病率较高相符。综述文章显示病例系列的偏倚风险较低，病例报告为中等，横断面研究为低。
本系统评价中考虑的研究表明，影像学特征可能足以识别病变并提供定期影像学随访。然而，值得注意的是，通过种植体进行口腔修复规划时需要CBCT，以尽量减少此类并发症的风险。
