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群组远程康复改善帕金森病患者的生活质量:一项双臂非平行非随机临床试验。

Group tele-rehabilitation improves quality of life among subjects with Parkinson's disease: A two arm non-parallel non-randomized clinical trial.

机构信息

Department of Physiotherapy, Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation, Maharishi Markandeshwar (Deemed to be University), Mullana, 133207, Ambala, Haryana, India.

Department of Physiotherapy, Modi University of Science and Technology, Laxmangarh, Sikar, 332311, Rajasthan, India.

出版信息

Parkinsonism Relat Disord. 2024 Apr;121:106027. doi: 10.1016/j.parkreldis.2024.106027. Epub 2024 Feb 10.

DOI:10.1016/j.parkreldis.2024.106027
PMID:38377657
Abstract

INTRODUCTION

Tele-rehabilitation has lately emerged as a promising medium for increasing patient adherence with significant positive results. One of the most prevalent neurological diseases affecting movement is Parkinson's disease (PD), which causes a variety of motor and non-motor symptoms among patients. Consequentially, the study was designed to compare the efficacy of group tele-rehabilitation with individual tele-rehabilitation in improving quality of life (QoL) among subjects with PD.

METHOD

A two-group pretest-posttest, non-randomized clinical study recruited 68 subjects and classified them into two groups, i.e., Group A (group therapy, n = 36) and Group B (individual therapy, n = 32). Groups A and B received a supervised protocol consisting of a 40-min session on alternate days/week for twelve weeks via the WhatsApp Messenger application through group and individual therapy, respectively. The Parkinson's disease questionnaire (PDQ-39), mental and physical components of the Short Form Survey (SF-12) were used as primary outcome variables, while the Satisfaction questionnaire was used as a secondary outcome variable.

RESULT

The p-values related to within-group analyses were <0.05 except SF-12 PCS >0.05 in Group A and <0.05 in Group B. While the p-values related to between-group analyses were <0.05 except for pre-scores of SF-12 (MCS and PCS). The effect sizes for PDQ-39, SF-12 (MCS), and SF-12 (PCS) were -2.37, 3.36, and 0.66 in Group A and 1.95, 2.69, and 2.03 in Group B, respectively.

CONCLUSION

The study concluded that group tele-rehabilitation is more effective in improving QoL among subjects with PD as compared to individual tele-rehabilitation. Clinical trial Registration NoCTRI/2022/04/041818.

摘要

介绍

远程康复最近作为一种提高患者依从性的有前途的手段出现,并取得了显著的积极成果。影响运动的最常见神经疾病之一是帕金森病(PD),它会导致患者出现多种运动和非运动症状。因此,本研究旨在比较小组远程康复和个体远程康复对改善 PD 患者生活质量(QoL)的效果。

方法

采用两组前后测试、非随机临床试验,招募了 68 名受试者,并将其分为两组,即 A 组(小组治疗,n=36)和 B 组(个体治疗,n=32)。两组均接受监督方案,通过 WhatsApp 信使应用程序分别进行小组和个体治疗,每周隔一天进行 40 分钟的治疗,共进行 12 周。帕金森病问卷(PDQ-39)、短表单调查(SF-12)的心理和身体成分作为主要结局变量,而满意度问卷作为次要结局变量。

结果

组内分析的 p 值<0.05,除了 A 组的 SF-12 PCS>0.05 和 B 组的所有 p 值<0.05。而组间分析的 p 值<0.05,除了 SF-12(MCS 和 PCS)的预评分。A 组的 PDQ-39、SF-12(MCS)和 SF-12(PCS)的效应量分别为-2.37、3.36 和 0.66,B 组分别为 1.95、2.69 和 2.03。

结论

研究得出结论,与个体远程康复相比,小组远程康复更能有效改善 PD 患者的生活质量。临床试验注册号:NCT04/2022/04/041818。

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