Wanless I R, Geddie W R
Arch Pathol Lab Med. 1985 Mar;109(3):283-6.
Lipogranulomata (LG) are commonly seen in human tissues but the location and significance of these lesions are incompletely documented. In a study of 465 autopsies LG were found in 48% of livers and 46% of spleens. Hepatic LG were more common in portal tracts than adjacent to the terminal hepatic venules. There was a close correlation between hepatic LG in liver and in spleen. The incidence and severity of hepatic LG were higher in older adults, especially men. There was no evidence that LG caused hepatic dysfunction or portal hypertension. The absence of correlation with hepatic steatosis supports the suggestion that LG are secondary to mineral oil deposition rather than to steatosis.
脂肪肉芽肿（LG）在人体组织中较为常见，但这些病变的位置和意义尚未完全记录在案。在一项对465例尸检的研究中，48%的肝脏和46%的脾脏中发现了LG。肝内LG在门静脉区比肝终末小静脉附近更为常见。肝脏和脾脏中的肝内LG之间存在密切相关性。老年人尤其是男性的肝内LG发病率和严重程度更高。没有证据表明LG会导致肝功能障碍或门静脉高压。与肝脂肪变性缺乏相关性支持了LG是矿物油沉积继发而非脂肪变性的观点。
