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两例罕见的Buschke-Löwenstein肿瘤病例报告。

A Report of Two Rare Cases of Buschke-Löwenstein Tumor.

作者信息

Bouhout Tariq, Ramdani Abdelbassir, Kharkhach Ayoub, Serji Badr

机构信息

Surgical Oncology, Mohammed VI University Hospital, Regional Oncology Center, Oujda, MAR.

出版信息

Cureus. 2024 Jan 21;16(1):e52700. doi: 10.7759/cureus.52700. eCollection 2024 Jan.

DOI:10.7759/cureus.52700
PMID:38384644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10879842/
Abstract

The Buschke-Löwenstein tumor is a rare clinical entity. Its severity is related to the local invasion and the risk of recurrence and malignant transformation. It is caused by a viral infection due to the human papillomavirus. The transmission is primarily sexual and often affects the penile region. The perineal location is relatively rare. We report two rare cases of neglected Buschke-Löwenstein tumor due to the late diagnosis treated with large surgical resection. This study aimed to emphasize the contribution of clinical examination in the early diagnosis and the management of our patients.

摘要

Buschke-Löwenstein肿瘤是一种罕见的临床实体。其严重程度与局部侵袭以及复发和恶变风险相关。它由人乳头瘤病毒引起的病毒感染所致。传播主要通过性途径，且常累及阴茎部位。会阴部位相对少见。我们报告两例因诊断延迟而被忽视的Buschke-Löwenstein肿瘤罕见病例，采用大手术切除进行治疗。本研究旨在强调临床检查在患者早期诊断和管理中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/097d8a76801e/cureus-0016-00000052700-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/ddfdfe1d2a11/cureus-0016-00000052700-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/c478a42a2fb2/cureus-0016-00000052700-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/abe7224454e6/cureus-0016-00000052700-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/88c6ad6bcbf2/cureus-0016-00000052700-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/182bb51108e4/cureus-0016-00000052700-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/097d8a76801e/cureus-0016-00000052700-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/ddfdfe1d2a11/cureus-0016-00000052700-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/c478a42a2fb2/cureus-0016-00000052700-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/abe7224454e6/cureus-0016-00000052700-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/88c6ad6bcbf2/cureus-0016-00000052700-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/182bb51108e4/cureus-0016-00000052700-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9347/10879842/097d8a76801e/cureus-0016-00000052700-i06.jpg

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本文引用的文献

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The Pathogenesis of Giant Condyloma Acuminatum (Buschke-Lowenstein Tumor): An Overview.巨大型尖锐湿疣（Buschke-Lowenstein 肿瘤）的发病机制：概述。
Int J Mol Sci. 2022 Apr 20;23(9):4547. doi: 10.3390/ijms23094547.
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Buschke-Löwenstein tumors: A series of 7 case reports.Buschke-Löwenstein肿瘤：7例病例报告系列
Exp Ther Med. 2022 Jun;23(6):393. doi: 10.3892/etm.2022.11320. Epub 2022 Apr 13.
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Clinicopathologic features of Buschke-Löwenstein tumor: a multi-institutional analysis of 38 cases. Buschke-Löwenstein 肿瘤的临床病理特征：38 例多机构分析。
Virchows Arch. 2020 Apr;476(4):543-550. doi: 10.1007/s00428-019-02680-z. Epub 2019 Nov 15.
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Verrucous carcinoma arising in an extended giant condyloma acuminatum (Buschke-Löwenstein tumor): a case report and review of the literature.发生于巨大型尖锐湿疣（Buschke-Löwenstein瘤）的疣状癌：一例报告并文献复习
J Med Case Rep. 2013 Dec 19;7:273. doi: 10.1186/1752-1947-7-273.
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Management of peri-anal giant condyloma acuminatum--a case report and literature review.肛周巨大尖锐湿疣的处理——附病例报告及文献复习。
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[Giant scrotal condyloma acuminata: a case report].[巨大阴囊尖锐湿疣：一例报告]
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