钕钇铝石榴石激光照射后正常大鼠脑组织的组织学研究。I. 大脑半球。

Histologic study of normal rat brain tissue after neodymium-yttrium aluminum garnet laser irradiation. I. Cerebral hemisphere.

作者信息

Yamagami T, Handa H, Takeuchi J, Hashimoto N, Taki W, Yonekawa Y

出版信息

Surg Neurol. 1985 May;23(5):475-82. doi: 10.1016/0090-3019(85)90242-3.

Abstract

We report a histologic study of normal rat brain tissue after neodymium-yttrium aluminum garnet laser irradiation. Morphological changes occurred at a maximum depth of 5 mm after 60-W, 1-second exposure, at a 2-mm distance between the optical fiber tip and the brain surface. Polymorphonuclear leukocyte infiltration into the irradiated area was observed 48 hours after irradiation. After 72 hours, macrophages and fibroblasts appeared; their number increased thereafter. At 1 month, tissue defects attributable to neodymium-yttrium aluminum garnet laser irradiation were small. Gliotic changes were rarely seen. We conclude that 60-W irradiation is harmful to young rats but not to adult rats.

摘要

我们报告了钕钇铝石榴石激光照射后正常大鼠脑组织的组织学研究。在功率60瓦、照射1秒、光纤尖端与脑表面距离为2毫米的情况下，最大深度5毫米处出现了形态学变化。照射后48小时观察到多形核白细胞浸润到照射区域。72小时后，出现了巨噬细胞和成纤维细胞；此后它们的数量增加。1个月时，钕钇铝石榴石激光照射导致的组织缺损较小。很少见到胶质细胞增生性变化。我们得出结论，60瓦的照射对幼鼠有害，但对成年大鼠无害。