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识别机器人辅助膀胱切除术行体内心外尿流改道术和体外线外尿流改道术围手术期结局的风险因素。

Identify risk factors for perioperative outcomes in Intracorporeal Urinary Diversion and Extracorporeal Urinary Diversion with Robotic Cystectomy.

机构信息

Department of Urology, University of Louisville School of Medicine, Louisville, KY, United States.

Case Western Urology Institute, University Hospital Cleveland Medical Center, Cleveland OH, United States.

出版信息

Int Braz J Urol. 2024 Mar-Apr;50(2):178-191. doi: 10.1590/S1677-5538.IBJU.2023.0477.

Abstract

INTRODUCTION

The increasing adoption of robotic-assisted cystectomy with intracorporeal urinary diversion (ICUD), despite its complexity, prompts a detailed comparison with extracorporeal urinary diversion (ECUD). Our study at a single institution investigates perioperative outcomes and identifies risk factors impacting the success of these surgical approaches.

METHODS

In this retrospective analysis, 174 patients who underwent robotic-assisted cystectomy at the University of Louisville from June 2016 to August 2021 were reviewed. The cohort was divided into two groups based on the urinary diversion method: 30 patients underwent ECUD and 144 underwent ICUD. Data on demographics, complication rates, length of hospital stay, and readmission rates were meticulously collected and analyzed.

RESULTS

Operative times were comparable between the ICUD and ECUD groups. However, the ICUD group had a significantly lower intraoperative transfusion rate (0.5 vs. 1.0, p=0.02) and shorter hospital stay (7.8 vs. 12.3 days, p<0.001). Factors such as male sex, smoking history, diabetes mellitus, intravesical therapy, higher ASA, and ACCI scores were associated with increased Clavien-Dindo Grade 3 or higher complications. Age over 70 was the sole factor linked to a higher 90-day readmission rate, with no specific characteristics influencing the 30-day rate.

CONCLUSION

Robotic cystectomy with ICUD results in shorter hospitalizations and lower intraoperative transfusion rates compared to ECUD, without differences in operative time, high-grade postoperative complications, or readmission rates. These findings can inform clinical decision-making, highlighting ICUD as a potentially more favorable option in appropriate settings.

摘要

简介

尽管机器人辅助膀胱切除术联合体内尿路分流术(ICUD)具有复杂性,但它的采用率正在不断增加。这促使我们对其与体外尿路分流术(ECUD)进行详细比较。我们在一家机构进行的研究调查了围手术期的结果,并确定了影响这些手术方法成功的风险因素。

方法

在这项回顾性分析中,我们回顾了 2016 年 6 月至 2021 年 8 月在路易斯维尔大学接受机器人辅助膀胱切除术的 174 名患者。根据尿路分流方法,将队列分为两组:30 名患者接受 ECUD,144 名患者接受 ICUD。详细收集并分析了人口统计学数据、并发症发生率、住院时间和再入院率。

结果

ICUD 组和 ECUD 组的手术时间相当。然而,ICUD 组的术中输血率明显较低(0.5%比 1.0%,p=0.02),住院时间较短(7.8 天比 12.3 天,p<0.001)。男性、吸烟史、糖尿病、膀胱内治疗、较高的 ASA 和 ACCI 评分等因素与 Clavien-Dindo 分级 3 或更高的并发症发生率增加相关。70 岁以上的年龄是与 90 天再入院率较高相关的唯一因素,而 30 天的再入院率没有特定的影响因素。

结论

与 ECUD 相比,机器人辅助膀胱切除术联合 ICUD 可导致住院时间缩短,术中输血率降低,而手术时间、术后高分级并发症和再入院率无差异。这些发现可以为临床决策提供信息,强调在适当的情况下,ICUD 可能是一种更有利的选择。

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