Quantum Materials and Devices Unit, Institute of Nano Science and Technology, Mohali, Punjab 140306, India.
Biological Science, St. John's University, New York, NY 10301, United States.
Nanoscale. 2024 Mar 14;16(11):5458-5486. doi: 10.1039/d3nr05648a.
Cancer has been classified as a diverse illness with a wide range of subgroups. Its early identification and prognosis, which have become a requirement of cancer research, are essential for clinical treatment. Patients have already benefited greatly from the use of artificial intelligence (AI), machine learning (ML), and deep learning (DL) algorithms in the field of healthcare. AI simulates and combines data, pre-programmed rules, and knowledge to produce predictions. Data are used to improve efficiency across several pursuits and tasks through the art of ML. DL is a larger family of ML methods based on representational learning and simulated neural networks. Support vector machines, convulsion neural networks, and artificial neural networks, among others, have been widely used in cancer research to construct prediction models that enable precise and effective decision-making. Although using these innovative methods can enhance our comprehension of how cancer progresses, further validation is required before these techniques can be used in routine clinical practice. We cover contemporary methods used in the modelling of cancer development in this article. The presented prediction models are built using a variety of guided ML approaches, as well as numerous input attributes and data collections. Early identification and cost-effective detection of cancer's progression are equally necessary for successful treatment of the disease. Smart material-based detection techniques can give end consumers a portable, affordable instrument to easily detect and monitor their health issues without the need for specialized knowledge. Owing to their cost-effectiveness, excellent sensitivity, multimodal detection capacity, and miniaturization aptitude, two-dimensional (2D) materials have a lot of prospects for clinical examination of various compounds as well as cancer biomarkers. The effectiveness of traditional devices is moving faster towards more useful techniques thanks to developments in 2D material-based biosensors/sensors. The most current developments in the design of 2D material-based biosensors/sensors-the next wave of cancer screening instruments-are also outlined in this article.
癌症已被归类为一种具有广泛亚群的多种疾病。其早期识别和预后已成为癌症研究的要求,对临床治疗至关重要。人工智能 (AI)、机器学习 (ML) 和深度学习 (DL) 算法在医疗保健领域的应用已经使患者受益匪浅。人工智能模拟和组合数据、预编程规则和知识以进行预测。通过 ML 的艺术,数据可用于提高多个追求和任务的效率。DL 是一个更大的 ML 方法家族,基于表示学习和模拟神经网络。支持向量机、卷积神经网络和人工神经网络等已广泛应用于癌症研究,以构建预测模型,实现精确有效的决策。尽管使用这些创新方法可以增强我们对癌症进展的理解,但在这些技术可用于常规临床实践之前,还需要进一步验证。本文涵盖了癌症发展建模中使用的当代方法。所提出的预测模型是使用各种有指导的 ML 方法以及众多输入属性和数据集构建的。早期识别和具有成本效益的癌症进展检测对于成功治疗疾病同样重要。基于智能材料的检测技术可以为最终消费者提供一种便携式、经济实惠的仪器,使他们能够轻松检测和监测自己的健康问题,而无需专业知识。由于其成本效益、出色的灵敏度、多模态检测能力和微型化能力,二维 (2D) 材料在临床检查各种化合物以及癌症生物标志物方面具有广阔的前景。由于基于 2D 材料的生物传感器/传感器的发展,传统设备的有效性正在朝着更有用的技术快速发展。本文还概述了基于 2D 材料的生物传感器/传感器设计的最新进展,即下一代癌症筛查仪器。