Department of Internal Medicine, Gastroenterology, and Pneumology, Brüderkrankenhaus St. Josef Paderborn, Husener Straße 46, 33098 Paderborn, Germany.
Department of Medicine, Gastroenterology, and Infectiology, University Hospital Muenster, Albert-Schweitzer-Campus 1 (A14), 48149 Muenster, Germany.
Int J Environ Res Public Health. 2024 Feb 17;21(2):235. doi: 10.3390/ijerph21020235.
(1) Background: Post-COVID syndrome is defined as symptoms that occur simultaneously with or after a COVID-19 infection, last for 12 weeks, and are not due to another diagnosis. Limited data are available on people's long-term quality of life following a COVID-19 infection. The aim of this cross-sectional study was to investigate the long-term quality of life after COVID-19 among employees of a hospital in Germany and to identify risk factors. (2) Methods: A monocentric, cross-sectional study was conducted using the validated and digitized WHOQOL-BREF questionnaire via Netigate® between 10/2022 and 02/2023. Data on the quality of life and global health status were collected in the following four domains: physical health, mental health, social relationships, and the environment. (3) Results: The response rate was 73.8 % (923/1250). Furthermore, 63.4 % of the hospital staff respondents reported at least one persistent symptom after a COVID-19 infection, leading to significant differences in quality of life. Pre-existing conditions, persistent symptoms, and disabilities after a COVID-19 infection as well as a high BMI, no partnership, and a low educational level were found to significantly contribute to a low long-term quality of life. (4) Conclusions: Obesity, a lack of partnership, and a low level of education were independent risk factors for a lower quality of life post-COVID-19 infection in this cohort of hospital staff. Further multicenter studies are required to validate the incidence and their suitability as independent risk factors for post-COVID syndrome.
(1) 背景：新冠后综合征被定义为与 COVID-19 感染同时或之后出现、持续 12 周且并非由其他诊断引起的症状。关于 COVID-19 感染后人们的长期生活质量，现有数据有限。本横断面研究旨在调查德国一家医院员工 COVID-19 后的长期生活质量，并确定风险因素。(2) 方法：使用经过验证和数字化的世卫组织生活质量简表（WHOQOL-BREF）通过 Netigate® 于 2022 年 10 月至 2023 年 2 月进行单中心横断面研究。在以下四个领域收集生活质量和全球健康状况数据：身体健康、心理健康、社会关系和环境。(3) 结果：应答率为 73.8%（923/1250）。此外，63.4%的医院工作人员报告在 COVID-19 感染后至少有一种持续症状，导致生活质量显著下降。先前存在的疾病、持续症状和 COVID-19 感染后的残疾以及 BMI 高、没有伴侣和教育水平低被发现是导致长期生活质量低的显著因素。(4) 结论：在该医院工作人员队列中，肥胖、缺乏伴侣和教育水平低是 COVID-19 感染后生活质量较低的独立危险因素。需要进一步的多中心研究来验证其发生率及其作为新冠后综合征的独立危险因素的适用性。
