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解析外生殖器角质形成细胞皮肤肿瘤中人类乳头瘤病毒(HPV)的复杂关系:鲍温病和原位鳞状细胞癌的综合分析

Unraveling the Complex Nexus of Human Papillomavirus (HPV) in Extragenital Keratinocyte Skin Tumors: A Comprehensive Analysis of Bowen's Disease and In Situ Squamous-Cell Carcinoma.

作者信息

Conforti Claudio, Retrosi Chiara, Agozzino Marina, Dianzani Caterina, Nardon Ermanno, Oliveri Anselmo, Azzalini Eros, Guida Stefania, Pellacani Giovanni, Di Lella Giovanni, Rongioletti Franco, Zalaudek Iris, Bonin Serena

机构信息

IDI-IRCCS, Dermatological Research Hospital, 00167 Rome, Italy.

Dermatology Clinic, Maggiore Hospital, Piazza Ospitale 1, 34125 Trieste, Italy.

出版信息

J Clin Med. 2024 Feb 15;13(4):1091. doi: 10.3390/jcm13041091.

Abstract

This comprehensive study delves into the intricate landscape surrounding the role of human papillomavirus (HPV) in extragenital keratinocyte skin tumors, specifically exploring Bowen's disease (BD) and in situ squamous-cell carcinoma (iSCC). Through a multifaceted examination, this research study elucidates the nuanced interplay of HPV, gender dynamics, anatomical site variations, and potential implications for the etiopathogenesis of these malignancies.

摘要

这项综合性研究深入探讨了人乳头瘤病毒(HPV)在生殖器外角质形成细胞皮肤肿瘤中的复杂作用,特别研究了鲍恩病(BD)和原位鳞状细胞癌(iSCC)。通过多方面的研究,该研究阐明了HPV、性别差异、解剖部位差异以及这些恶性肿瘤发病机制的潜在影响之间的细微相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b72/10889444/08efebdaba5a/jcm-13-01091-g001.jpg

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