Adam Cloé, Colin Marius, Stock Romuald, Weiss Laurent, Gangloff Sophie C
Université de Reims Champagne-Ardenne, UR 4691 Biomatériaux et Inflammation en Site Osseux (BIOS), UFR de Pharmacie, SFR CAP-Santé, 51 rue Cognacq Jay, 51100 Reims, France.
Université de Lorraine, LCOMS, EA7306 Lorraine, France.
Life (Basel). 2024 Feb 16;14(2):256. doi: 10.3390/life14020256.
Disinfection in the hospital environment remains challenging, especially for wide and structurally complex objects such as beds or wheelchairs. Indeed, the regular disinfection of these objects with chemicals is manually carried out by healthcare workers and is fastidious and time-consuming. Alternative antibacterial techniques were thus proposed in the past decades, including the use of naturally antimicrobial UVC. Here, the antibacterial efficiency of a large UVC box built to accommodate wheelchairs was investigated through testing bacterial burden reductions on various parts of a wheelchair, with various support types and with several treatment durations. The results demonstrate a time-dependent antibacterial effect, with a strong burden reduction at only five minutes of treatment (>3-log median reduction in and ). The UVC flux and residual bacterial burden both significantly varied depending on the spatial location on the wheelchair. However, the nature of the support impacted the antibacterial efficiency even more, with residual bacterial burdens being the lowest on rigid materials (steel, plastics) and being the highest on tissue. On metallic samples, the nature of the alloy and surface treatment had various impacts on the antibacterial efficiency of the UVC. This study highlights the efficiency of the tested UVC box to efficiently and quickly decontaminate complex objects such as wheelchairs, but also gives rise to the warning to focus on rigid materials and avoid porous materials in the conception of objects, so as to ensure the efficiency of UVC decontamination.
医院环境中的消毒工作仍然具有挑战性，尤其是对于床或轮椅等大型且结构复杂的物体。事实上，医护人员手动使用化学药剂对这些物体进行定期消毒既繁琐又耗时。因此，在过去几十年里人们提出了替代抗菌技术，包括使用具有天然抗菌作用的紫外线C（UVC）。在此，通过测试轮椅不同部位、不同支撑类型以及不同处理时长下细菌载量的减少情况，对一个为容纳轮椅而建造的大型UVC箱的抗菌效率进行了研究。结果表明了一种时间依赖性抗菌效果，仅处理五分钟就有显著的载量减少（在[具体部位1]和[具体部位2]中中位数减少超过3个对数）。UVC通量和残余细菌载量均因轮椅上的空间位置不同而有显著差异。然而，支撑物的性质对抗菌效率的影响更大，刚性材料（钢、塑料）上的残余细菌载量最低，而织物上的最高。在金属样品上，合金的性质和表面处理对UVC的抗菌效率有不同影响。本研究突出了所测试的UVC箱对轮椅等复杂物体进行高效快速去污的效率，但同时也警示在物体设计时要关注刚性材料并避免使用多孔材料，以确保UVC去污的效率。
