Division of Chest Medicine, Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 2, Min-Sheng Road, Dalin, Chiayi 62247, Taiwan.
Medicina (Kaunas). 2024 Jan 26;60(2):211. doi: 10.3390/medicina60020211.
There are few data on the effects of prolonged mechanical ventilation on elderly patients. Our objective is to investigate the effects of prolonged mechanical ventilation on older patients' successful weaning and long-term survival. We examined how aging affected the course and results of elderly patients on prolonged mechanical ventilation by contrasting five age groups. Age, sex, cause of acute respiratory failure, comorbidities, discharge status, weaning status, and long-term survival outcomes were among the information we gathered. Patients on prolonged mechanical ventilation who had undergone tracheostomy and had been successfully weaned had a greater one-year survival rate. The 1-year survival rate was poorer for older patients with four or more comorbidities. Regarding the 5-year survival rate, the risk of death was 45% lower in the successfully weaned patients than in the unsuccessfully weaned patients. The risk of death was 46% lower in patients undergoing tracheostomy than in those not undergoing tracheostomy. Older prolonged mechanical ventilation (PMV) patients with four or more comorbidities had an increased risk of death. When it comes to elderly patients on prolonged mechanical ventilation, there are other factors in addition to age that influence long-term survival. Long-term survival is likewise linked to successful weaning and undergoing tracheostomy.
关于长时间机械通气对老年患者的影响的数据较少。我们的目的是研究长时间机械通气对老年患者成功撤机和长期生存的影响。我们通过对比五个年龄组来研究年龄对长时间机械通气老年患者病程和结果的影响。我们收集的信息包括年龄、性别、急性呼吸衰竭的原因、合并症、出院状态、撤机状态和长期生存结果。接受气管切开和成功撤机的长时间机械通气患者的一年生存率更高。有四种或更多合并症的老年患者一年生存率较差。关于 5 年生存率,成功撤机患者的死亡风险比未成功撤机患者低 45%。接受气管切开的患者的死亡风险比未接受气管切开的患者低 46%。有四种或更多合并症的长时间机械通气(PMV)老年患者死亡风险增加。对于长时间机械通气的老年患者,除了年龄之外,还有其他因素影响长期生存。长期生存同样与成功撤机和接受气管切开有关。