Bennett Brady W, Phillips Lawrence S, Gazmararian Julie A
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
Atlanta VA Medical Center, Decatur, GA 30033, USA.
Vaccines (Basel). 2024 Jan 30;12(2):145. doi: 10.3390/vaccines12020145.
Disparities in vaccination coverage for coronavirus disease 2019 (COVID-19) in the United States (U.S.) are consistent barriers limiting our ability to control the spread of disease, particularly those by age and race/ethnicity. This study examines the association between previous vaccination for common adult infectious diseases and vaccination for SARS-CoV-2 among a cohort of veterans in the U.S. Sociodemographic and clinical data were utilized from three databases within the Veterans Health Administration included in the electronic health record. We examined the association of previous vaccination for common adult vaccinations through six separate multivariable logistic regression analyses, one for each previous vaccine exposure, adjusting for demographic and clinical variables. We also examined the association of receiving any one of the six common adult vaccinations and vaccination against SARS-CoV-2. Adjusted models indicate higher odds of vaccination for SARS-CoV-2 among those who received each of the previous vaccinations. Significant differences were also noted by race/ethnicity and age. Veterans who recorded receiving any one of the previous vaccinations for common adult infections had significantly greater odds of receiving any vaccination against SARS-CoV-2. Understanding veterans' previous vaccination status can assist researchers and clinicians in impacting the uptake of novel vaccines, such as vaccination against SARS-CoV-2.
美国2019冠状病毒病(COVID-19)疫苗接种覆盖率的差异一直是限制我们控制疾病传播能力的障碍,尤其是按年龄和种族/族裔划分的差异。本研究在美国一组退伍军人中,考察了既往常见成人传染病疫苗接种与严重急性呼吸综合征冠状病毒2(SARS-CoV-2)疫苗接种之间的关联。社会人口统计学和临床数据来自退伍军人健康管理局电子健康记录中的三个数据库。我们通过六项单独的多变量逻辑回归分析,考察了既往常见成人疫苗接种的关联,每种既往疫苗接种情况各进行一次分析,并对人口统计学和临床变量进行了调整。我们还考察了接种六种常见成人疫苗中的任何一种与接种SARS-CoV-2疫苗之间的关联。调整后的模型显示,既往接种过每种疫苗的人群接种SARS-CoV-2疫苗的几率更高。在种族/族裔和年龄方面也发现了显著差异。记录显示接种过任何一种既往常见成人感染疫苗的退伍军人接种任何SARS-CoV-2疫苗的几率显著更高。了解退伍军人既往的疫苗接种状况有助于研究人员和临床医生影响新型疫苗的接种率,例如SARS-CoV-2疫苗的接种。