Altern Ther Health Med. 2024 Oct;30(10):404-408.
Rheumatoid arthritis (RA) is a chronic autoimmune disorder affecting joint health and patients' overall well-being. While methotrexate (MTX) is a standard therapeutic intervention, enhancing its efficacy with pain-specific nursing remains underexplored.
This study aims to assess the impact of combining MTX with pain-specific nursing on patients with RA, providing valuable insights for clinical practice and offering an improved therapeutic approach to alleviate pain and enhance the overall quality of life for affected individuals.
We conducted a prospective cohort study, choosing a cohort of 86 RA patients admitted to our hospital from March 2021 to March 2023. After treatment, we compared the number of swollen and painful joints, duration of morning stiffness, and scores on the Visual Analogue Scale (VAS), Pittsburgh Sleep Quality Index (PSQI), and Self-rating Anxiety Scale/Self-rating Depression Scale (SAS/SDS) between the two groups. Nursing satisfaction was surveyed upon discharge, and patient quality of life was assessed using the 36-item Short Form Health Survey (SF-36).
The research group exhibited a notable decrease in the number of swollen and painful joints, significantly shorter morning stiffness duration, and marked reductions in VAS, PSQI, SAS, and SDS scores compared to the control group (P < .05). Additionally, nursing satisfaction and SF-36 scores were higher in the research group (P < .05).
The combination of MTX and pain-specific nursing effectively alleviated pain and improved the quality of life and nursing satisfaction among RA patients.
类风湿关节炎（RA）是一种影响关节健康和患者整体健康的慢性自身免疫性疾病。甲氨蝶呤（MTX）是一种标准的治疗干预措施，但与疼痛特异性护理相结合以提高其疗效仍未得到充分探索。
本研究旨在评估将 MTX 与疼痛特异性护理相结合对 RA 患者的影响，为临床实践提供有价值的见解，并提供一种改善的治疗方法，以减轻疼痛并提高受影响个体的整体生活质量。
我们进行了一项前瞻性队列研究，选择了 2021 年 3 月至 2023 年 3 月期间我院收治的 86 例 RA 患者作为队列。治疗后，我们比较了两组患者肿胀和疼痛关节的数量、晨僵持续时间、视觉模拟量表（VAS）、匹兹堡睡眠质量指数（PSQI）和焦虑自评量表/抑郁自评量表（SAS/SDS）评分。出院时进行护理满意度调查，并使用 36 项简明健康状况调查问卷（SF-36）评估患者的生活质量。
研究组肿胀和疼痛关节数量明显减少，晨僵持续时间明显缩短，VAS、PSQI、SAS 和 SDS 评分明显降低，与对照组相比差异有统计学意义（P<0.05）。此外，研究组的护理满意度和 SF-36 评分较高（P<0.05）。
MTX 联合疼痛特异性护理可有效缓解 RA 患者的疼痛，提高生活质量和护理满意度。
