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后光学区直径对角膜塑形术治疗区面积和轴向伸长的影响。

The effect of the back optic zone diameter on the treatment zone area and axial elongation in orthokeratology.

机构信息

Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, China; State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, China; School of Ophthalmology, Shandong First Medical University, China.

Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, China; State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, China; School of Ophthalmology, Shandong First Medical University, China.

出版信息

Cont Lens Anterior Eye. 2024 Apr;47(2):102131. doi: 10.1016/j.clae.2024.102131. Epub 2024 Feb 25.

Abstract

PURPOSE

To investigate the influence of corneal parameters on the treatment zone area (TZA) after Corneal Refractive Therapy (CRT) with a 5.0-mm back optical zone diameter (BOZD) were worn and to compare changes in the axial length (AL) with traditional 6.0-mm BOZD lenses.

METHODS

This retrospective study involved 146 subjects (7-12 years) who wore orthokeratology (ortho-K) lenses for one year: 86 subjects were treated with CRT 5.0-mm lenses, and 60 subjects were treated with CRT 6.0-mm lenses. The TZA was measured after one year of ortho-K treatment. Both TZA and AL elongation after wearing the two kinds of lenses was compared. The parameters were recorded in the CRT 5.0 group: flat K, steep K, corneal toricity, e value, and anterior corneal elevation values at the 3-, 4-, and 5-mm chords along the principal meridians of the superior, inferior, nasal, and temporal sides. The relationships between these data and the TZA were analyzed.

RESULTS

The TZA was 12.90 ± 5.15 mm and 20.61 ± 4.54 mm, and the AL elongation was 0.15 ± 0.18 mm and 0.26 ± 0.18 mm in the CRT 5.0 group and the CRT 6.0 group, respectively (all p < 0.001). The one-year AL elongation was significantly associated with initial age and the TZA (r =  - 0.394, 0.393; all p < 0.001) in the CRT 5.0 group. The following corneal parameters were found to have statistically significant correlations with the TZA: the e value, difference in corneal elevation (nasal-temporal at the 3-, 4-, and 5-mm chord), and the absolute value of elevation difference (nasal-temporal at the 3- and 4-mm chord and inferior-superior at the 3-, 4-, and 5-mm chord). The e value was the only relevant factor for the TZA by multiple regression analysis (unstandardized β = 14.219, p = 0.008). In the CRT 6.0 group, the one-year AL elongation was statistically significantly associated only with initial age (r =  - 0.605, p = 0.005), but not with the TZA (p = 0.161).

CONCLUSIONS

A smaller TZA induced by a smaller BOZD may be beneficial for retarding AL elongation in children undergoing ortho-K treatment. The morphology and eccentricity of the cornea may show effects on the TZA.

摘要

目的

研究角膜参数对佩戴 5.0mm 后光学区直径(BOZD)角膜屈光矫正治疗(CRT)的治疗区面积(TZA)的影响,并比较传统 6.0mm BOZD 镜片的眼轴(AL)变化。

方法

本回顾性研究纳入了 146 名(7-12 岁)佩戴角膜塑形镜(ortho-K)一年的患者:86 名患者接受 CRT 5.0mm 镜片治疗,60 名患者接受 CRT 6.0mm 镜片治疗。在 ortho-K 治疗一年后测量 TZA。比较两种镜片佩戴后的 TZA 和 AL 伸长。在 CRT 5.0 组中记录了 TZA 和 AL 伸长:平 K 值、陡 K 值、角膜旋转、e 值以及在上方、下方、鼻侧和颞侧的主要子午线的 3、4 和 5mm 弦线上的前角膜隆起值。分析这些数据与 TZA 的关系。

结果

在 CRT 5.0 组和 CRT 6.0 组中,TZA 分别为 12.90±5.15mm 和 20.61±4.54mm,AL 伸长分别为 0.15±0.18mm 和 0.26±0.18mm(均 p<0.001)。在 CRT 5.0 组中,一年的 AL 伸长与初始年龄和 TZA 显著相关(r=-0.394,0.393;均 p<0.001)。与 TZA 有统计学显著相关性的角膜参数如下:e 值、角膜隆起差异(3、4 和 5mm 弦线上的鼻侧-颞侧)和隆起差异绝对值(3 和 4mm 弦线上的鼻侧-颞侧以及下方-上方的 3、4 和 5mm 弦线上)。e 值是多元回归分析中唯一与 TZA 相关的因素(未标准化β=14.219,p=0.008)。在 CRT 6.0 组中,一年的 AL 伸长仅与初始年龄显著相关(r=-0.605,p=0.005),与 TZA 无关(p=0.161)。

结论

佩戴较小 BOZD 引起的较小 TZA 可能有利于减缓儿童接受 ortho-K 治疗时的 AL 伸长。角膜的形态和偏心度可能会对 TZA 产生影响。

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