Ni Hai-Long, Chen Xiang, Chen Du-Ya, Hu Pei-Ke, Wu Zhi-Yi
Eye Center, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China.
Int J Ophthalmol. 2024 Oct 18;17(10):1843-1849. doi: 10.18240/ijo.2024.10.10. eCollection 2024.
To elucidate whether differences exist in the impact on retarding the elongation of axial length (AL) among children with myopia when utilizing orthokeratology (ortho-k) lenses employing the corneal refractive therapy (CRT) design versus those employing the vision shaping treatment (VST) design.
This retrospective clinical trial aimed to collect and analyze AL data from individuals who wore ortho-k lenses for three years. A total of 654 subjects were enrolled and prescribed one of the three specific brands of ortho-k lenses: CRT, Euclid, and Mouldway. The study's primary focus was to compare the rates of AL elongation and myopic progression across these three brands of ortho-k lenses.
In the 3-year follow-up, the AL elongation exhibited variations of 0.73±0.36 mm in the CRT lens group, 0.59±0.37 mm in the Euclid lens group, and 0.63±0.38 mm in the Mouldway lens group. A noteworthy disparity emerged between the CRT and Mouldway groups (<0.01), as well as between the CRT and Euclid groups (<0.001). Additionally, it was observed that 32.1% of participants who wore CRT lenses experienced a decelerated progression of myopia, in contrast to 47.2% in the Euclid group and 44.4% in the Mouldway group. Statistical analyses revealed a statistically significant distinction between the CRT and Euclid groups (<0.01), and similarly, the CRT group demonstrated a statistically significant difference when compared to the Mouldway group (<0.05).
Ortho-k lenses represent a pragmatic strategy for mitigating the advancement of myopia. In contradistinction to ortho-k lenses utilizing the CRT design, those employing the VST design exhibited a more favorable impact regarding retarding AL elongation.
阐明采用角膜屈光治疗(CRT)设计的角膜塑形术(ortho-k)镜片与采用视力塑形治疗(VST)设计的镜片在延缓近视儿童眼轴长度(AL)增长方面的影响是否存在差异。
这项回顾性临床试验旨在收集和分析佩戴ortho-k镜片三年的个体的AL数据。共招募了654名受试者,并为其开具了三种特定品牌的ortho-k镜片之一:CRT、欧几里得和模道。该研究的主要重点是比较这三种品牌的ortho-k镜片的AL伸长率和近视进展情况。
在3年的随访中,CRT镜片组的AL伸长率为0.73±0.36mm,欧几里得镜片组为0.59±0.37mm,模道镜片组为0.63±0.38mm。CRT组与模道组之间(<0.01)以及CRT组与欧几里得组之间(<0.001)出现了显著差异。此外,观察到佩戴CRT镜片的参与者中有32.1%的人近视进展减缓,而欧几里得组为47.2%,模道组为44.4%。统计分析显示CRT组与欧几里得组之间存在统计学显著差异(<0.01),同样,CRT组与模道组相比也显示出统计学显著差异(<0.05)。
角膜塑形术镜片是减缓近视进展的一种实用策略。与采用CRT设计的角膜塑形术镜片不同,采用VST设计的镜片在延缓AL伸长方面表现出更有利的影响。