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使用远端栓塞保护装置进行颈动脉支架置入术时的血流停滞:单中心经验及临床意义

Flow arrest during carotid artery stenting with a distal embolic protection device: A single-center experience and clinical implications.

作者信息

Hong Noah, Park Jeong-Mee, Kim Seung Bin, Son Young-Je

机构信息

Department of Neurosurgery, Seoul National University-Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea.

Department of Critical Care Medicine, Seoul National University-Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea.

出版信息

J Cerebrovasc Endovasc Neurosurg. 2024 Jun;26(2):163-173. doi: 10.7461/jcen.2024.E2023.10.001. Epub 2024 Feb 26.

Abstract

OBJECTIVE

We aimed to investigate the incidence of flow arrest during carotid artery stenting (CAS) with filter-type embolic protection device (EPD), identify any predisposing factors for those situations, and contemplate intraprocedural precautionary steps.

METHODS

CAS was performed in 128 patients with 132 arteries using filter-type EPD. The characteristics of treated patients and arteries were compared between groups with and without flow arrest.

RESULTS

The incidence of flow arrest during CAS with filter-type EPD was 17.4%. In flow arrest group, cases of vulnerable plaques (p=0.02) and symptomatic lesions (p=0.01) were significantly more common, and there were more cases of debris captured by EPD in a planar pattern (p<0.01). Vulnerable plaques were significantly more common in the procedures showing a planar pattern than in the cases with other patterns (p<0.01). Flow arrest group showed a significantly higher rate of ischemic complications (p<0.05), although there were no significant periprocedural neurological changes. The planar pattern of captured debris in filter-type EPD was the only significant risk factor for flow arrest (adjusted odds ratio 88.44, 95% confidence interval 15.21-514.45, p<0.05).

CONCLUSIONS

Flow arrest during CAS with filter-type EPD is not uncommon and associated with increased ischemic complications. Symptomatic stenoses and vulnerable plaque are related to this event. The planar pattern of captured debris on the EPD was the only significant risk factor for the flow arrest. Clinicians must pay attention to the occurrence of flow arrest and react quickly when performing CAS.

摘要

目的

我们旨在研究使用滤网式栓子保护装置(EPD)进行颈动脉支架置入术(CAS)期间血流停滞的发生率,确定这些情况的任何易感因素,并思考术中预防措施。

方法

使用滤网式EPD对128例患者的132条动脉进行CAS。比较有和没有血流停滞的组之间治疗患者和动脉的特征。

结果

使用滤网式EPD进行CAS期间血流停滞的发生率为17.4%。在血流停滞组中,易损斑块(p=0.02)和有症状病变(p=0.01)的病例明显更常见,并且EPD以平面模式捕获的碎片病例更多(p<0.01)。与其他模式的病例相比,在显示平面模式的手术中易损斑块明显更常见(p<0.01)。尽管围手术期没有明显的神经学变化,但血流停滞组的缺血性并发症发生率明显更高(p<0.05)。滤网式EPD中捕获碎片的平面模式是血流停滞的唯一显著危险因素(调整后的优势比88.44,95%置信区间15.21-514.45,p<0.05)。

结论

使用滤网式EPD进行CAS期间的血流停滞并不罕见,并且与缺血性并发症增加有关。有症状的狭窄和易损斑块与该事件有关。EPD上捕获碎片的平面模式是血流停滞的唯一显著危险因素。临床医生在进行CAS时必须注意血流停滞的发生并迅速做出反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c87/11220293/4875684d8558/jcen-2024-e2023-10-001f1.jpg

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