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[植入式脑机接口医学应用的伦理考量]

[Ethical considerations for medical applications of implantable brain-computer interfaces].

作者信息

Zhang Zhe, Chen Yanxiao, Zhao Xu, Wang Fan, Ding Peng, Zhao Lei, Fu Yunfa

机构信息

Faculty of Marxism, Kunming University of Science and Technology, Kunming 650500, P. R. China.

Brain Cognition and Brain-computer Intelligence Integration Group, Kunming University of Science and Technology, Kunming 650500, P. R. China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2024 Feb 25;41(1):177-183. doi: 10.7507/1001-5515.202309083.

Abstract

Implantable brain-computer interfaces (BCIs) have potentially important clinical applications due to the high spatial resolution and signal-to-noise ratio of electrodes that are closer to or implanted in the cerebral cortex. However, the surgery and electrodes of implantable BCIs carry safety risks of brain tissue damage, and their medical applications face ethical challenges, with little literature to date systematically considering ethical norms for the medical applications of implantable BCIs. In order to promote the clinical translation of this type of BCI, we considered the ethics of practice for the medical application of implantable BCIs, including: reducing the risk of brain tissue damage from implantable BCI surgery and electrodes, providing patients with customized and personalized implantable BCI treatments, ensuring multidisciplinary collaboration in the clinical application of implantable BCIs, and the responsible use of implantable BCIs, among others. It is expected that this article will provide thoughts and references for the research and development of ethics of the medical application of implantable BCI.

摘要

可植入式脑机接口(BCIs)因其电极具有较高的空间分辨率和信噪比,且电极更靠近大脑皮层或植入大脑皮层,因而具有潜在重要的临床应用价值。然而,可植入式脑机接口的手术和电极存在脑组织损伤的安全风险,其医学应用面临伦理挑战,目前鲜有文献系统地考虑可植入式脑机接口医学应用的伦理规范。为推动此类脑机接口的临床转化,我们考虑了可植入式脑机接口医学应用的实践伦理,包括:降低可植入式脑机接口手术和电极造成脑组织损伤的风险、为患者提供定制化和个性化的可植入式脑机接口治疗、确保可植入式脑机接口临床应用中的多学科协作以及对可植入式脑机接口的负责任使用等。期望本文能为可植入式脑机接口医学应用伦理的研究与发展提供思路和参考。

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