Xiong Junting, Feng Longfei, Liu Baolin, Wang Xin
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P. R. China.
Shanghai Technical Service Platform for Cryopreservation of Biological Resources, Shanghai 200093, P. R. China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2024 Feb 25;41(1):199-204. doi: 10.7507/1001-5515.202303022.
Methylcellulose is a semi-flexible cellulose ether derivative, whose hydrogels are thermosensitive and reversible, with good biocompatibility and adjustable function, and its application has attracted much attention in the biomedical field. In this paper, the application of methylcellulose-based thermo-sensitive hydrogels in biomedical field was reviewed. Based on the mechanism of gelation and influencing factors of methylcellulose, this paper focused on the recent advances in biomedical applications of methylcellulose-based hydrogels, including drug delivery, regenerative medicine, and other related fields. The current achievements in these fields were summarized in the form of lists in this paper to provide ideas and tendencies for future research. Finally, the future development of multifunctional methylcellulose-based hydrogel materials with improved performance was also discussed.
甲基纤维素是一种半柔性纤维素醚衍生物，其水凝胶具有热敏性和可逆性，具有良好的生物相容性和可调节功能，其应用在生物医学领域备受关注。本文综述了甲基纤维素基热敏水凝胶在生物医学领域的应用。基于甲基纤维素的凝胶化机制和影响因素，本文重点介绍了甲基纤维素基水凝胶在生物医学应用方面的最新进展，包括药物递送、再生医学及其他相关领域。本文以列表形式总结了这些领域的当前成果，为未来研究提供思路和趋势。最后，还讨论了性能改进的多功能甲基纤维素基水凝胶材料的未来发展。
