General Surgery Federal Govt Polyclinic Hospital Islamabad.
Akbar Niazi Teaching Hospital, Islamabad, Pakistan.
J Ayub Med Coll Abbottabad. 2023 Jul-Sep;35(3):371-374. doi: 10.55519/JAMC-03-12158.
A surgical site infection (SSI) is a wound infection caused by pathogens, particularly bacteria, that occurs within 30 days of the surgery. Various methods have been employed to minimise infection rates of infection one of which is intra-operative wound irrigation. This study aims to compare the frequency of surgical site infections after wound irrigation of contaminated and dirty wounds with normal saline and aqueous povidone-iodine solutions.
This randomized controlled trial was carried out in the surgical department of Federal Government Polyclinic Hospital from January to December 2022. A total of 180 patients were randomly divided into two equal groups using blocked randomization. Group A had normal saline irrigation while Group B had aqueous povidone-iodine irrigation before surgical incision closure. Patients were followed till 30th post-operative day. Data was collected, entered and analyzed using SPSS 20.0.
A total of 180 patients were recruited in this study, equally divided into Group A and Group B with 90 patients each. Fifty-three patients (58.9%) from group-A and 58 patients (64.4%) from group-B were having contaminated wounds and 37 patients (41.1%) and 32 patients (35.6%) had dirty wounds respectively. Surgical site infection was found in 29 patients (32.2%) of group-A and 26 patients (28.8%) of group-B (p=0.627). there was no significant difference between the two groups concerning surgical site infection.
Irrigation of surgical wounds with aqueous povidone-iodine solution before primary closure was statistically similar to normal saline in preventing surgical site infections in contaminated and dirty wounds.
手术部位感染（SSI）是指手术后 30 天内由病原体（尤其是细菌）引起的伤口感染。为了降低感染率，人们采用了各种方法，其中一种是术中伤口冲洗。本研究旨在比较用生理盐水和聚维酮碘溶液冲洗污染和脏污伤口的手术部位感染频率。
本随机对照试验于 2022 年 1 月至 12 月在联邦政府综合医院外科进行。采用区组随机化将 180 例患者分为两组，每组 90 例。A 组用生理盐水冲洗，B 组在手术切口关闭前用聚维酮碘溶液冲洗。患者随访至术后 30 天。使用 SPSS 20.0 收集、输入和分析数据。
本研究共纳入 180 例患者，平均分为 A 组和 B 组，每组 90 例。A 组 53 例（58.9%）患者为污染伤口，B 组 58 例（64.4%）患者为污染伤口，A 组 37 例（41.1%）和 B 组 32 例（35.6%）患者为脏污伤口。A 组有 29 例（32.2%）患者发生手术部位感染，B 组有 26 例（28.8%）患者发生手术部位感染（p=0.627）。两组手术部位感染发生率无统计学差异。
在污染和脏污伤口中，与生理盐水相比，在一期缝合前用聚维酮碘溶液冲洗手术伤口在预防手术部位感染方面并无统计学差异。
