Departments of Rheumatology and Nephrology, Prince of Wales Hospital, Sydney, New South Wales, Australia.
Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
Intern Med J. 2024 Mar;54(3):483-487. doi: 10.1111/imj.16343. Epub 2024 Feb 25.
There have been reports of COVID-19 vaccination triggering anti-nuclear cytoplasmic antibody (ANCA)-associated vasculitis (AAV), but no robust studies have examined the link. This retrospective cohort study assessed the impact of COVID vaccination on the rate of denovo and relapsed AAV in a Sydney Local Health District from 2018 to 2022. Despite more than 95% of the population receiving vaccination, the case rate of AAV was stable. These findings do not support a relationship between COVID vaccination and AAV.
有报道称 COVID-19 疫苗接种可引发抗核细胞质抗体 (ANCA)-相关性血管炎 (AAV)，但尚无强有力的研究来检验两者之间的关联。这项回顾性队列研究评估了 2018 年至 2022 年期间悉尼地方卫生区 COVID 疫苗接种对新发和复发性 AAV 发生率的影响。尽管超过 95%的人群接受了疫苗接种，但 AAV 的发病率保持稳定。这些发现不支持 COVID 疫苗接种与 AAV 之间存在关系。
