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急性冠状动脉综合征患者焦虑和抑郁的患病率:系统评价和荟萃分析。

Prevalence of anxiety and depression in patients with acute coronary syndrome: systematic review and meta-analysis.

机构信息

Universidad Cesar Vallejo, Chiclayo, Perú.

Facultad de Ingeniería y Negocios, Universidad Norbert Wiener, Lima, Perú.

出版信息

Pan Afr Med J. 2023 Nov 26;46:91. doi: 10.11604/pamj.2023.46.91.41792. eCollection 2023.

DOI:10.11604/pamj.2023.46.91.41792
PMID:38405089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10891371/
Abstract

Depression and anxiety are common in patients experiencing acute coronary syndrome (ACS), occurring at significantly elevated rates. Together, these depressive symptoms and anxiety have a substantial negative impact on individuals with ACS. Therefore, the aim of the present study was to determine the prevalence of anxiety and depression among patients with ACS. A systematic review and meta-analysis of cross-sectional studies were carried out. A comprehensive search of five databases (PubMed, Scopus, Embase, Web of Science, and ScienceDirect) was performed until August 2, 2023. The quality of the included studies was assessed using the Joanna Briggs Institute statistical meta-analysis review instrument. The collected data were entered into a Microsoft Excel spreadsheet and analyzed with the R program version 4.2.3. A total of 3103 articles were evaluated, and, after the evaluation process, eight studies were included, for a total sample of 1642 participants. The pooled prevalence of mild depression was 14% (95% CI: 06%-23%; I= 95%), moderate was 12% (95% CI: 06%-19%; I= 92%), and high/severe was 15% (95% CI: 05%-30%; I= 97%). The joint prevalence of mild anxiety was 38% (95% CI: 12%-68%; I= 98%), moderate anxiety was 17% (95% CI: 08%-29%; I= 89%), and high/severe anxiety was 10% (95% CI: 01%-25%; I=95%). Therefore, it is concluded that there is a significant prevalence of anxiety and depressive symptoms in patients with ACS. However, more research focused on this area is required to obtain more robust and substantial evidence.

摘要

抑郁和焦虑在经历急性冠脉综合征(ACS)的患者中很常见,发生率明显升高。这些抑郁症状和焦虑共同对 ACS 患者产生了实质性的负面影响。因此,本研究旨在确定 ACS 患者中焦虑和抑郁的患病率。对横断面研究进行了系统评价和荟萃分析。对五个数据库(PubMed、Scopus、Embase、Web of Science 和 ScienceDirect)进行了全面搜索,截至 2023 年 8 月 2 日。使用 Joanna Briggs 研究所统计荟萃分析审查工具评估纳入研究的质量。将收集到的数据输入 Microsoft Excel 电子表格,并使用 R 程序版本 4.2.3 进行分析。共评估了 3103 篇文章,经过评估过程,纳入了 8 项研究,共有 1642 名参与者的总样本。轻度抑郁的合并患病率为 14%(95%CI:06%-23%;I=95%),中度为 12%(95%CI:06%-19%;I=92%),重度为 15%(95%CI:05%-30%;I=97%)。轻度焦虑的合并患病率为 38%(95%CI:12%-68%;I=98%),中度焦虑为 17%(95%CI:08%-29%;I=89%),重度焦虑为 10%(95%CI:01%-25%;I=95%)。因此,可以得出结论,ACS 患者中存在明显的焦虑和抑郁症状患病率。然而,需要更多关注该领域的研究,以获得更稳健和实质性的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adac/10891371/c421b0a3a056/PAMJ-46-91-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adac/10891371/c421b0a3a056/PAMJ-46-91-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adac/10891371/c421b0a3a056/PAMJ-46-91-g001.jpg

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