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[肝素诱导的抗凝血酶III缺乏症与先天性蛋白C缺乏症。附病例报告]

[Antithrombin III deficiency induced by heparin and constitutional protein C deficiency. Apropos of a case].

作者信息

Vergoz D, Kannapel M F, Hieaux C, Dentan T

出版信息

Phlebologie. 1985 Jul-Sep;38(3):425-7.

PMID:3840598
Abstract

Major mesenteric venous thrombosis in a young man who had already had spontaneous thromboembolic accidents prompted the diagnosis in 1982 of 'Antithromin III' deficiency. The initial reduction of this inhibitor proved to be secondary to a consumption raised abnormally by Heparin. Research into the family antecedents made it possible in 1983 to discover a constitutional 'Protein C' deficiency without stopping the antivitamins K for this patient.

摘要

一名年轻男性曾发生过自发性血栓栓塞事件,1982年因出现严重的肠系膜静脉血栓形成而诊断为“抗凝血酶III”缺乏症。最初该抑制剂水平降低被证明是由于肝素异常增加了其消耗所致。对家族病史的调查使得在1983年发现该患者存在先天性“蛋白C”缺乏,且当时并未停用维生素K拮抗剂。

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