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脱发性毛囊炎的成功治疗

Successful Management of Folliculitis Decalvans.

作者信息

Kashikar Yash, Saoji Vikrant, Madke Bhushan, Chandak Meenakshi S, Meghe Soham

机构信息

Dermatology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research (DMIHER) (Deemed University), Wardha, IND.

出版信息

Cureus. 2024 Jan 24;16(1):e52881. doi: 10.7759/cureus.52881. eCollection 2024 Jan.

DOI:10.7759/cureus.52881
PMID:38406166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10894017/
Abstract

Folliculitis decalvans (FD) is a rare disease that causes inflammation on the scalp, leading to scarring alopecia. It commonly affects young and middle-aged men and is characterized by pustules, papules, scarring, hemorrhagic crusts, and erosions. The exact cause of FD is not fully understood, but it is believed that may play a role in its development. The condition is thought to be influenced by a combination of genetic, allergic, infectious, and immunological factors. This report describes a 20-year-old male patient who experienced painful pustules on his scalp for six months. The pustules first appeared on the occipital region and then spread to the crown. The patient was diagnosed with FD after a thorough clinical and pus culture examination. Treatment involved a month-long prescription of doxycycline (100 mg BD) and topical ozenoxacin (2%), which led to successful remission of the lesions.

摘要

脱发性毛囊炎(FD)是一种罕见疾病,可导致头皮炎症,进而引起瘢痕性脱发。它通常影响中青年男性,其特征为脓疱、丘疹、瘢痕、出血性结痂和糜烂。FD的确切病因尚未完全明确,但据信[此处原文缺失内容]可能在其发病过程中起作用。该病被认为受遗传、过敏、感染和免疫因素的综合影响。本报告描述了一名20岁男性患者,其头皮出现疼痛性脓疱6个月。脓疱最初出现在枕部区域,随后蔓延至头顶。经过全面的临床和脓液培养检查后,该患者被诊断为FD。治疗包括为期一个月的多西环素(100毫克,每日两次)处方和外用奥昔沙星(2%),这使得皮损成功缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/5c22af5d6a24/cureus-0016-00000052881-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/22ec63556abc/cureus-0016-00000052881-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/9b12cdcc0e55/cureus-0016-00000052881-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/6929b1cb62dd/cureus-0016-00000052881-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/73a529db20af/cureus-0016-00000052881-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/5c22af5d6a24/cureus-0016-00000052881-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/22ec63556abc/cureus-0016-00000052881-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/9b12cdcc0e55/cureus-0016-00000052881-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/6929b1cb62dd/cureus-0016-00000052881-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/73a529db20af/cureus-0016-00000052881-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5117/10894017/5c22af5d6a24/cureus-0016-00000052881-i05.jpg

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本文引用的文献

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Updates in therapeutics for folliculitis decalvans: A systematic review with evidence-based analysis.脱发性毛囊炎的治疗进展:一项基于证据分析的系统评价
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In vitro antimicrobial activity of ozenoxacin against methicillin-susceptible Staphylococcus aureus, methicillin-resistant S. aureus and Streptococcus pyogenes isolated from clinical cutaneous specimens in Japan.奥扎沙星对从日本临床皮肤标本中分离出的甲氧西林敏感金黄色葡萄球菌、耐甲氧西林金黄色葡萄球菌和化脓性链球菌的体外抗菌活性。
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Retrospective Review of Folliculitis Decalvans in 23 Patients with Course and Treatment Analysis of Long-standing Cases.
23例脱发性毛囊炎患者的回顾性研究及长期病例的病程与治疗分析
J Cutan Med Surg. 2015 Jan-Feb;19(1):45-9. doi: 10.2310/7750.2014.13218. Epub 2015 Jan 1.
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Effective treatment of folliculitis decalvans using selected antimicrobial agents.使用选定的抗菌药物有效治疗脱发性毛囊炎。
Int J Trichology. 2010 Jan;2(1):20-3. doi: 10.4103/0974-7753.66908.
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Immunopathogenesis of folliculitis decalvans: clues in early lesions.脱发性毛囊炎的免疫发病机制:早期病变中的线索
Am J Clin Pathol. 2008 Oct;130(4):526-34. doi: 10.1309/NG60Y7V0WNUFH4LA.
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Tetracyclines: nonantibiotic properties and their clinical implications.四环素类:非抗生素特性及其临床意义。
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