Department of Radiology, School of Medicine, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, United States.
Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.
Br J Radiol. 2024 May 29;97(1158):1067-1077. doi: 10.1093/bjr/tqae048.
This review aims to serve as a foundational resource for general radiologists, enhancing their understanding of the role of Magnetic Resonance Imaging (MRI) in early prognostication for newborns diagnosed with hypoxic ischaemic encephalopathy (HIE). The article explores the application of MRI as a predictive instrument for determining long-term outcomes in newborns affected by HIE. With HIE constituting a leading cause of neonatal mortality and severe long-term neurodevelopmental impairments, early identification of prognostic indicators is crucial for timely intervention and optimal clinical management. We examine current literature and recent advancements to provide an in-depth overview of MRI predictors, encompassing brain injury patterns, injury scoring systems, spectroscopy, and diffusion imaging. The potential of these MRI biomarkers in predicting long-term neurodevelopmental outcomes and the probability of epilepsy is also discussed.
这篇综述旨在为普通放射科医生提供一个基础资源,增强他们对磁共振成像(MRI)在诊断为缺氧缺血性脑病(HIE)的新生儿早期预后中的作用的理解。本文探讨了 MRI 在预测 HIE 新生儿长期结局中的应用。由于 HIE 是新生儿死亡和严重长期神经发育障碍的主要原因,因此早期识别预后指标对于及时干预和最佳临床管理至关重要。我们检查了当前的文献和最新进展,提供了对 MRI 预测因子的深入概述,包括脑损伤模式、损伤评分系统、光谱和弥散成像。还讨论了这些 MRI 生物标志物在预测长期神经发育结局和癫痫发生概率方面的潜力。