Walker R A, Hawkins R A, Miller W R
J Pathol. 1985 Oct;147(2):103-6. doi: 10.1002/path.1711470205.
A series of breast carcinomas of known steroid receptor status have been examined for evidence of binding of the lectins peanut agglutinin, soy bean agglutinin and wheat germ agglutinin. Correlations were found between oestrogen receptor status and reactivity of carcinomas to peanut agglutinin and soy bean agglutinin but these were not absolute. Wheat germ agglutinin binding was unrelated to the presence of oestrogen receptors. No relationship was evident between progestogen receptors and the binding of any lectin. It therefore seems unlikely that lectin histochemistry can replace steroid receptors as markers of hormone dependence in breast carcinomas.
对一系列已知类固醇受体状态的乳腺癌进行了检测，以寻找凝集素花生凝集素、大豆凝集素和麦胚凝集素结合的证据。发现雌激素受体状态与癌组织对花生凝集素和大豆凝集素的反应性之间存在相关性，但并非绝对相关。麦胚凝集素结合与雌激素受体的存在无关。孕激素受体与任何凝集素的结合之间没有明显关系。因此，凝集素组织化学似乎不太可能取代类固醇受体作为乳腺癌激素依赖性的标志物。
