Department of Pain and Rehabilitation, The Second Affiliated Hospital, University of South China, Hengyang, Hunan, 421001, China.
BMC Anesthesiol. 2024 Feb 26;24(1):77. doi: 10.1186/s12871-024-02426-8.
Extensive metastatic and refractory cancer pain is common, and exhibits a dissatisfactory response to the conventional intrathecal infusion of opioid analgesics.
The present study reports a case of an extensive metastatic esophageal cancer patient with severe intractable pain, who underwent translumbar subarachnoid puncture with intrathecal catheterization to the prepontine cistern. After continuous infusion of low-dose morphine, the pain was well-controlled with a decrease in the numeric rating scale (NRS) of pain score from 9 to 0, and the few adverse reactions to the treatment disappeared at a low dose of morphine.
The patient achieved a good quality of life during the one-month follow-up period.
广泛转移性和难治性癌痛很常见，对常规鞘内输注阿片类镇痛药的反应不佳。
本研究报告了一例广泛转移性食管痛患者，该患者疼痛剧烈且难以控制，行腰穿蛛网膜下腔置管至脑桥前池。给予小剂量吗啡持续输注后，疼痛得到很好的控制，数字评分量表（NRS）评分从 9 分降至 0 分，且不良反应少，吗啡剂量低。
在一个月的随访期间，患者生活质量良好。
