Campbell K A, Evans G, Gallistel C R
Physiol Behav. 1985 Sep;35(3):395-403. doi: 10.1016/0031-9384(85)90315-4.
Determination of the function relating rate of pressing to the number of pulses in a train of fixed duration (the rate-frequency function) yields a physiologically interpretable measure of changes in the rewarding efficacy of the stimulation, because the number of action potentials in the reward-relevant first stage axons is directly proportional to the number of pulses in the train. We describe a system, based on a low cost microcomputer, which permits determination of 16-data-point rate-frequency functions in 4-6 animals simultaneously in less than 10 minutes. We give an empirical and theoretical justification for using the curve-shift measurement procedure in drug and lesion work, where the experimental treatments must be presumed to have substantial effects on performance factors.
确定在固定持续时间的一串脉冲中按压速率与脉冲数量之间的函数关系（速率 - 频率函数），可以得出对刺激奖赏效力变化的一种生理学上可解释的测量指标，因为与奖赏相关的第一级轴突中的动作电位数量与这串脉冲中的脉冲数量成正比。我们描述了一种基于低成本微型计算机的系统，该系统能够在不到10分钟的时间内同时测定4 - 6只动物的16个数据点的速率 - 频率函数。我们为在药物和损伤研究中使用曲线移位测量程序提供了经验和理论依据，在这些研究中，必须假定实验处理对行为因素有实质性影响。
