Yamamoto T, Oomura Y, Nishino H, Aou S, Nakano Y
J Neurosci Methods. 1985 May;13(3-4):281-94. doi: 10.1016/0165-0270(85)90076-7.
Computerized control of a bar-press feeding task initiated by a monkey's vocalization was designed to study the motivational roles of brain regions in feeding behavior. In this paradigm, the monkey was required to vocalize in order to initiate the task and then press the bar 30 times to obtain the reward. A microcomputer was used to sense the vocalization and to control the task. Using this system, changes in single neuron activity in the orbitofrontal cortex and the lateral hypothalamic area preceding the time of the vocalization were observed. The entire system including interface and control program is described.