Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria.
Department of Obstetrics and Gynaecology, College of Medicine, University of Nigeria, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria.
Niger J Clin Pract. 2024 Feb 1;27(2):228-235. doi: 10.4103/njcp.njcp_634_23. Epub 2024 Feb 26.
In the past five years, observational evidence suggests that the rates and determinants of preterm birth may have changed due to the effect of the coronavirus disease 2019 (COVID-19) pandemic and other humanitarian crises in our environment.
This study aimed to determine the incidence, associated factors, and outcomes of preterm birth in tertiary hospitals in Enugu, southeastern Nigeria.
This cross-sectional study included 238 pregnant women from the University of Nigeria Teaching Hospital (UNTH), Enugu State University of Science and Technology Teaching Hospital (ESUT-TH) Parklane, and Mother of Christ Specialist Hospital (MOCSH), Enugu, from April 2022 to March 2023. Eligible and consenting participants were recruited from 28-36 weeks +6 days of gestational age and followed up until delivery. Relevant outcome variables, such as sociodemographic characteristics, gestational age at delivery, and pregnancy outcomes, were recorded in a pro forma. These data were analyzed using IBM Statistical Package for the Social Sciences (SPSS) statistics for Windows, version 22.0, Armonk, NY: IBM Corp.
The incidence of preterm birth was 16.6% (37/223), with spontaneous preterm birth constituting 24 of 37 (64.5%) cases. The mean age of participants was 30.3 ± 4.8 years. Advanced maternal age (>35 years) (P = 0.01, adjusted odds ratio (AOR) =0.01, confidence interval (CI): 0.00-0.144), low socioeconomic status (P = 0.04, AOR = 0.40, CI: 0.11-1.46), and history of miscarriage (P = 0.02, AOR = 0.06, CI: 0.01-0.59) were the factors associated with spontaneous preterm birth. Neonatal death occurred in 21.6% (8/37) of cases within the first 24 hours. Rates of cesarean section and low birth weight were 73% (27/37) each.
The incidence of preterm birth is high in Enugu, and associated factors were advanced maternal age, low socioeconomic status, and a history of miscarriage.
在过去五年中，观察性证据表明，由于 2019 年冠状病毒病（COVID-19）大流行和我们环境中的其他人道主义危机的影响，早产的发生率和决定因素可能已经发生了变化。
本研究旨在确定尼日利亚东南部埃努古州 tertiary 医院早产的发生率、相关因素和结局。
本横断面研究纳入了 2022 年 4 月至 2023 年 3 月期间来自尼日利亚大学教学医院（UNTH）、埃努古州科技大学教学医院（ESUT-TH）Parklane 和圣母玛利亚专科医院（MOCSH）的 238 名孕妇。纳入标准为妊娠 28-36 周+6 天且同意参加研究的孕妇，并随访至分娩。记录相关结局变量，如社会人口学特征、分娩时的孕周和妊娠结局，并在表格中记录。使用 IBM 统计软件包（SPSS） for Windows 版本 22.0（Armonk，NY：IBM Corp.）对这些数据进行分析。
早产发生率为 16.6%（37/223），自发性早产占 37 例中的 24 例（64.5%）。参与者的平均年龄为 30.3±4.8 岁。高龄产妇（>35 岁）（P=0.01，调整后的优势比（AOR）=0.01，置信区间（CI）：0.00-0.144）、社会经济地位低（P=0.04，AOR=0.40，CI：0.11-1.46）和流产史（P=0.02，AOR=0.06，CI：0.01-0.59）是与自发性早产相关的因素。在 24 小时内，有 21.6%（8/37）的新生儿死亡。剖宫产和低出生体重的发生率分别为 73%（27/37）。
埃努古的早产发生率较高，相关因素为高龄产妇、社会经济地位低和流产史。
