Department of Chemistry, Kanya Gurukul Campus, Gurukula Kangri (Deemed to be University), Haridwar, 249407, Uttarakhand, India.
Department of Chemistry, Gurukula Kangri (Deemed to be University), Haridwar, 249404, Uttarakhand, India.
Chem Biodivers. 2024 Apr;21(4):e202302124. doi: 10.1002/cbdv.202302124. Epub 2024 Mar 12.
Ficus drupacea is a medicinal tree found in temperate regions. Various parts of this plant had been used traditionally for the treatment of various ailments such as root powder applied externally for skin infections. Analysis was carried out on the bioactive lipids extracted from Ficus drupacea fruit using both petroleum-based solvent (Hexane) and an environmentally friendly solvent Dimethyl carbonate (DMC). The results showed that DMC extraction yielded a high oil content in Ficus drupacea fruit (6.51 %). When examining the fatty acid composition using GC-FID analysis, Ficus drupacea oil extracted with DMC contained significant proportions of essential fatty acids such as linoleic acid (32.317 %), oleic acid (20.946 %), palmitic acid (25.841 %), etc. Additionally, DMC extraction resulted in higher levels of total phenolics in Ficus drupacea fruit oil compared to hexane. Moreover, DMC extracted oil exhibited stronger antioxidant properties, such as radical scavenging, anti- arthritic, photoprotective activity while displayed similar anti-inflammatory and anti-microbial activity as hexane-extracted oil. In summary, these findings demonstrate that DMC is an efficient and safer alternative to conventional solvent hexane for extracting oils from Ficus drupacea fruit. It is rich in bioactive compounds essential for human nutrition, including polyunsaturated fatty acids, flavonoids, and phenolic compounds, with enhanced biological activities.
无忧树是一种生长在温带地区的药用树木。该植物的各个部分一直以来都被传统地用于治疗各种疾病，例如将根部粉末外敷用于治疗皮肤感染。本研究采用石油基溶剂（己烷）和环保溶剂二甲基碳酸酯（DMC）对无忧树果实中的生物活性脂质进行了提取分析。结果表明，DMC 提取法能够从无忧树果实中获得高油含量（6.51％）。通过 GC-FID 分析脂肪酸组成，发现 DMC 提取的无忧树油中含有大量必需脂肪酸，如亚油酸（32.317％）、油酸（20.946％）、棕榈酸（25.841％）等。此外，与己烷相比，DMC 提取的无忧树籽油中总酚含量更高。而且，DMC 提取的油表现出更强的抗氧化性能，如自由基清除、抗关节炎、光保护活性，同时表现出与己烷提取的油相似的抗炎和抗菌活性。总之，这些研究结果表明，DMC 是从无忧树果实中提取油的有效且更安全的替代传统溶剂己烷的方法。它富含对人类营养至关重要的生物活性化合物，包括多不饱和脂肪酸、类黄酮和酚类化合物，具有增强的生物活性。
