Ranjan Rahul, Gunasekaran Jayanthi, Bir Raunak, Kumar Umesh, Gupta Rajiv M
Department of Microbiology, ESIC Medical College and Hospital, Faridabad, IND.
Cureus. 2024 Jan 27;16(1):e53035. doi: 10.7759/cureus.53035. eCollection 2024 Jan.
is a type of bacteria that can cause infections in both immunocompromised and immunocompetent hosts. It is an obligate aerobe and is commonly found in the environment. Pulmonary nocardiosis may present as pneumonia, endobronchial inflammatory masses, lung abscess, and cavitary disease with contiguous extension, leading to effusion and empyema. We present a case of pulmonary nocardiosis in a 75-year-old male patient with type 2 diabetes mellitus. The patient presented with bilateral pneumonia and hypoxia with an oxygen saturation of 85%. Sputum samples were sent to the microbiology laboratory for testing. Acid-fast staining with 1% HSO showed acid-fast branching filamentous rods, but could not be isolated in culture. The sample was subjected to 16S rRNA gene sequencing, which identified the pathogen as . The culture of the sputum did not grow any pathogenic organisms, and the blood culture was sterile. Unfortunately, the patient left the hospital against medical advice as he was advised for intubation. The patient could not survive and died the next day after leaving the hospital. can be fatal and cause disseminated infection in both immunosuppressed and immunocompetent patients. Only eight case reports of have been reported in the literature from various parts of the world. Our case is the first case report of from India.
是一种可在免疫功能低下和免疫功能正常的宿主中引起感染的细菌类型。它是专性需氧菌，常见于环境中。肺诺卡菌病可表现为肺炎、支气管内炎性肿块、肺脓肿以及伴有邻近组织扩展的空洞性疾病，导致胸腔积液和脓胸。我们报告一例75岁2型糖尿病男性患者的肺诺卡菌病病例。该患者表现为双侧肺炎和低氧血症，血氧饱和度为85%。痰液样本被送至微生物实验室进行检测。用1%硫酸处理的抗酸染色显示抗酸分支丝状杆菌，但在培养中未能分离出。对样本进行16S rRNA基因测序，鉴定病原体为。痰液培养未生长任何致病生物，血培养无菌。不幸的是，患者在被建议插管时自行出院。患者未能存活，出院次日死亡。可导致致命性感染，并在免疫抑制和免疫功能正常的患者中引起播散性感染。世界各地的文献中仅报道了8例病例报告。我们的病例是来自印度的首例病例报告。
