Roy Moni, Martial Annia, Ahmad Sharjeel
Department of Internal Medicine, University of Illinois College of Medicine, Peoria, Illinois, USA and OSF Saint Francis Medical Center, Peoria, Illinois, USA.
Department of Internal Medicine, University of Illinois College of Medicine, Peoria, Illinois, USA.
Eur J Case Rep Intern Med. 2020 Sep 9;7(11):001904. doi: 10.12890/2020_001904. eCollection 2020.
is a genus of aerobic, non-motile and non-spore-forming filamentous branching bacteria with fragmentation into bacillary or coccoid forms. Infections caused by often occur in immunocompromised hosts and are potentially life-threatening. has rarely been reported to cause infection in immunocompetent hosts. We present a case of disseminated infection due to in a patient with no known medical comorbidities, who presented with new-onset seizure. Another interesting finding in our case is that our patient did not have any pulmonary symptoms despite chest CT showing the pulmonary system as the likely primary site of infection. As per our literature review, this is the seventh reported case of infection due to in an immunocompetent host.
To recognize , a slow-growing weakly acid-fast filamentous bacteria commonly causing opportunistic infections in immunocompromised hosts, as an emerging pathogen in immunocompetent patients.Tissue biopsy with Gram staining showing variable filamentous bacteria and confirmation of species using restriction enzyme analysis and 16S rRNA analysis is needed to establish a diagnosis of infection.Trimethoprim/sulfamethoxazole has been successfully used to treat infection due to .
是需氧、无运动性、不形成芽孢的丝状分支细菌属，可断裂成杆菌或球菌形式。由其引起的感染常发生于免疫功能低下的宿主，且可能危及生命。很少有报道称其在免疫功能正常的宿主中引起感染。我们报告一例在无已知内科合并症的患者中因该菌导致播散性感染的病例，该患者出现新发癫痫。我们病例中的另一个有趣发现是，尽管胸部CT显示肺部系统可能是主要感染部位，但我们的患者没有任何肺部症状。根据我们的文献综述，这是第七例报道的免疫功能正常宿主因该菌感染的病例。
认识到是一种生长缓慢的弱抗酸丝状细菌，通常在免疫功能低下的宿主中引起机会性感染，也是免疫功能正常患者中的一种新兴病原体。需要进行组织活检，革兰氏染色显示可变丝状细菌，并使用限制性内切酶分析和16S rRNA分析来确认菌种，以确立感染的诊断。甲氧苄啶/磺胺甲恶唑已成功用于治疗因该菌引起的感染。
