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小儿恙虫病感染的神经学表现:来自印度中部三级医疗医院的病例报告

Neurological Manifestations of Scrub Typhus Infection in Pediatric Patient: A Case Report From Tertiary Care Hospital in Central India.

作者信息

Singh Priyanka, Shete Vishal, Choudhary Abhijit, Gade Neeta, Mishra Meena

机构信息

Department of Microbiology, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.

Department of Pediatrics, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.

出版信息

Cureus. 2024 Jan 27;16(1):e53060. doi: 10.7759/cureus.53060. eCollection 2024 Jan.

DOI:10.7759/cureus.53060
PMID:38410352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10896270/
Abstract

Scrub typhus is a neglected tropical bacterial disease endemic in central India which can manifest as meningitis/meningoencephalitis in children. It is difficult to diagnose clinically, especially in the absence of eschar or rash. Scrub typhus is seldom considered the differential diagnosis of meningitis in the Indian subcontinent. Appropriate investigations can lead to early detection of infection and initiation of correct antibiotic treatment leading to better patient prognosis even when features of meningitis supervene. Here, we report a pediatric case of scrub typhus meningitis that could be saved due to timely investigations and initiation of appropriate antimicrobial agents.

摘要

恙虫病是一种被忽视的热带细菌性疾病,在印度中部地区流行,可在儿童中表现为脑膜炎/脑膜脑炎。临床上很难诊断,尤其是在没有焦痂或皮疹的情况下。在印度次大陆,恙虫病很少被视为脑膜炎的鉴别诊断。即使在出现脑膜炎症状时,进行适当的检查也能早期发现感染并开始正确的抗生素治疗,从而改善患者预后。在此,我们报告一例小儿恙虫病脑膜炎病例,由于及时检查并开始使用适当的抗菌药物,该患儿得以救治。

相似文献

1
Neurological Manifestations of Scrub Typhus Infection in Pediatric Patient: A Case Report From Tertiary Care Hospital in Central India.小儿恙虫病感染的神经学表现:来自印度中部三级医疗医院的病例报告
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本文引用的文献

1
Association of Scrub Typhus in Children with Acute Encephalitis Syndrome and Meningoencephalitis, Southern India.印度南部儿童丛林斑疹伤寒与急性脑炎综合征和脑膜脑炎的关联。
Emerg Infect Dis. 2023 Apr;29(4):711-722. doi: 10.3201/eid2904.221157.
2
The burden of scrub typhus in India: A systematic review.印度恙虫病负担:系统评价。
PLoS Negl Trop Dis. 2021 Jul 27;15(7):e0009619. doi: 10.1371/journal.pntd.0009619. eCollection 2021 Jul.
3
Clinical manifestations of scrub typhus.恙虫病的临床表现。
Trans R Soc Trop Med Hyg. 2017 Feb 1;111(2):43-54. doi: 10.1093/trstmh/trx017.
4
Differential diagnosis of scrub typhus meningitis from bacterial meningitis using clinical and laboratory features.恙虫病性脑膜炎与细菌性脑膜炎的临床和实验室特征鉴别诊断。
Neurol India. 2013 Jan-Feb;61(1):17-20. doi: 10.4103/0028-3886.107919.
5
Scrub typhus: the geographic distribution of phenotypic and genotypic variants of Orientia tsutsugamushi.恙虫病:恙虫病东方体表型和基因型变异的地理分布
Clin Infect Dis. 2009 Mar 15;48 Suppl 3:S203-30. doi: 10.1086/596576.