生物钟节律由果蝇起搏神经元氯离子振荡调节。
Circadian Rhythm Regulation by Pacemaker Neuron Chloride Oscillation in Flies.
机构信息
Molecular Medicine Program, University of Utah, Salt Lake City, Utah, United States.
Department of Internal Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, Utah, United States.
出版信息
Physiology (Bethesda). 2024 May 1;39(3):0. doi: 10.1152/physiol.00006.2024. Epub 2024 Feb 27.
Abstract
Circadian rhythms in physiology and behavior sync organisms to external environmental cycles. Here, circadian oscillation in intracellular chloride in central pacemaker neurons of the fly, , is reviewed. Intracellular chloride links SLC12 cation-coupled chloride transporter function with kinase signaling and the regulation of inwardly rectifying potassium channels.
摘要
生理和行为中的昼夜节律使生物体与外部环境周期同步。本文回顾了果蝇中央起搏器神经元中的细胞内氯离子的昼夜振荡。细胞内氯离子将 SLC12 阳离子偶联氯离子转运体的功能与激酶信号以及内向整流钾通道的调节联系起来。
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