School of Public Health, Sun Yat-Sen University, No. 74, 2nd Zhongshan Road, Guangzhou, Guangdong, China.
Greater Bay Area Public Health Research Collaboration, Guangzhou, China.
Sci Rep. 2024 Feb 27;14(1):4729. doi: 10.1038/s41598-024-54378-1.
To examine the association of adverse childhood experiences (ACEs) with anemia among older people. 24,116 participants aged 50 years or above were recruited. Multivariable linear and logistic regression was used to assess the associations of self-reported ACEs number with hemoglobin concentrations (g/dL) and presence of anemia. Older individuals with two or more ACEs, versus no ACEs, showed lower hemoglobin concentrations (β = - 0.08 g/dL, 95% confidence intervals (CI) - 0.12 to - 0.03) and higher odds of anemia (odds ratio = 1.26, 95% CI 1.01-1.59). A more pronounced association between ACEs and anemia in the lower education group was found, while the association became non-significant in those with higher education (P for ACEs-education interaction = 0.02). ACEs was associated with anemia in older people, and the association was stronger in those with lower education, highlighting the significance of early-life psychological stressors assessment and consideration of education background in geriatric care.
探讨老年人不良童年经历（ACEs）与贫血之间的关联。共招募了 24116 名年龄在 50 岁及以上的参与者。采用多变量线性和逻辑回归评估自我报告 ACE 数量与血红蛋白浓度（g/dL）和贫血存在之间的关联。与无 ACE 者相比，有 2 个或更多 ACE 者的血红蛋白浓度较低（β=−0.08 g/dL，95%置信区间（CI）为−0.12 至−0.03），贫血的几率更高（比值比=1.26，95%CI 为 1.01-1.59）。在受教育程度较低的人群中，ACEs 与贫血之间的关联更为显著，而在受教育程度较高的人群中，这种关联变得不显著（ACEs-教育交互作用的 P 值=0.02）。ACEs 与老年人贫血相关，且在受教育程度较低的人群中相关性更强，这突显了在老年护理中评估早期生活心理压力源和考虑教育背景的重要性。
