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使用A型肉毒杆菌毒素治疗全膝关节置换术后腘绳肌引起的屈曲挛缩:病例系列

Use of Botulinum Toxin A to Manage Hamstring-Induced Flexion Contracture Following Total Knee Arthroplasty: A Case Series.

作者信息

Cheesman Quincy T, Ponzio Danielle Y, Thalody Hope E, Lau Vincent W, Post Zachary D, Ong Alvin

机构信息

Orthopedic Surgery, Jefferson Health New Jersey, Stratford, USA.

Orthopedic Surgery, Rothman Orthopedic Institute, Egg Harbor Township, USA.

出版信息

Cureus. 2024 Jan 28;16(1):e53113. doi: 10.7759/cureus.53113. eCollection 2024 Jan.

DOI:10.7759/cureus.53113
PMID:38414679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10898921/
Abstract

Introduction Flexion contractures following total knee arthroplasty (TKA) greatly affect patient function and satisfaction. Botulinum toxin A (BTX) has been described in the literature as a means of addressing post-operative flexion contractures due to hamstring muscle rigidity. Methods We retrospectively report a case series of eight patients with range of motion (ROM) who developed a flexion contracture status post-TKA and were managed with the use of physical therapy, diagnostic hamstring lidocaine injections, and therapeutic hamstring BTX injections. Results All patients had an improvement in extension ROM following diagnostic lidocaine hamstring injections and were therefore considered candidates for therapeutic hamstring BTX injections. Prior to therapeutic hamstring BTX injections, patients had an average flexion contracture of 19° (range: 15°-22°). All patients had an improvement in extension ROM two to four weeks following the therapeutic hamstring BTX injection, with an average improvement in ROM of 7° (range: 2°-19°). At the final follow-up, all patients continued to sustain an improvement in extension ROM with an average deficit of 9° (range: 0°-17°). Conclusion Our case series highlights the use of diagnostic hamstring lidocaine injections to confirm hamstring rigidity as an etiology for flexion contracture following TKA. In addition, we showed a persistent improvement in flexion contracture for all patients after hamstring BTX injections. Therefore, when the appropriate patient is selected, BTX may provide an additional treatment option for a flexion contracture following TKA.

摘要

引言 全膝关节置换术(TKA)后出现的屈曲挛缩严重影响患者的功能和满意度。文献中已描述肉毒杆菌毒素A(BTX)可作为解决因腘绳肌僵硬导致的术后屈曲挛缩的一种方法。方法 我们回顾性报告了一组8例患者的病例系列,这些患者在TKA后出现活动范围(ROM)问题并发展为屈曲挛缩,接受了物理治疗、诊断性腘绳肌利多卡因注射以及治疗性腘绳肌BTX注射。结果 所有患者在诊断性腘绳肌利多卡因注射后伸直ROM均有改善,因此被认为是治疗性腘绳肌BTX注射的候选者。在进行治疗性腘绳肌BTX注射前,患者的平均屈曲挛缩为19°(范围:15° - 22°)。所有患者在治疗性腘绳肌BTX注射后2至4周伸直ROM均有改善,ROM平均改善7°(范围:2° - 19°)。在最后一次随访时,所有患者伸直ROM持续改善,平均缺损为9°(范围:0° - 17°)。结论 我们的病例系列突出了使用诊断性腘绳肌利多卡因注射来确认腘绳肌僵硬是TKA后屈曲挛缩的病因。此外,我们显示所有患者在腘绳肌BTX注射后屈曲挛缩持续改善。因此,当选择合适的患者时,BTX可能为TKA后屈曲挛缩提供一种额外的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6b3/10898921/074eb88426f2/cureus-0016-00000053113-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6b3/10898921/074eb88426f2/cureus-0016-00000053113-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6b3/10898921/074eb88426f2/cureus-0016-00000053113-i01.jpg

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Efficacy of manipulation under anesthesia beyond three months following total knee arthroplasty.全膝关节置换术后三个月以上进行麻醉下手法治疗的疗效
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Manipulation under anesthesia following total knee arthroplasty: a comprehensive review of literature.
全膝关节置换术后麻醉下手法治疗:文献综述
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Efficacy of Manipulation Under Anesthesia for Stiffness Following Total Knee Arthroplasty: A Systematic Review.麻醉下手法松解治疗全膝关节置换术后僵硬的疗效:系统评价。
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Patient Dissatisfaction Following Total Knee Arthroplasty: A Systematic Review of the Literature.全膝关节置换术后患者的不满:文献系统评价。
J Arthroplasty. 2017 Dec;32(12):3854-3860. doi: 10.1016/j.arth.2017.07.021. Epub 2017 Jul 21.
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What is the Ideal Degree of Extension After Primary Total Knee Arthroplasty?初次全膝关节置换术后理想的伸直角度是多少?
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