Suppr超能文献

诊断性神经阻滞预测脑卒中后痉挛性马蹄内翻足肉毒毒素治疗的结局:一项回顾性观察研究。

Diagnostic nerve block in prediction of outcome of botulinum toxin treatment for spastic equinovarus foot after stroke: A retrospective observational study.

机构信息

Department of Neurosciences, Biomedicine and Movement Sciences,, University of Verona, IT-37134 Verona, Italy. E-mail:

出版信息

J Rehabil Med. 2020 Jun 12;52(6):jrm00069. doi: 10.2340/16501977-2693.

Abstract

OBJECTIVE

To evaluate the role of diagnostic nerve block in predicting the outcome of subsequent botulinum toxin type A treatment for spastic equinovarus foot due to chronic stroke.

DESIGN

Retrospective observational study.

PATIENTS

Fifty chronic stroke patients with spastic equinovarus foot.

METHODS

Each patient was given diagnostic tibial nerve block (lidocaine 2% perineural injection) assessment followed by botulinum toxin type A inoculation into the same muscles as had been targeted by the nerve block. All patients were evaluated before diagnostic nerve block, after the nerve block, and 4 weeks after botulinum toxin injection. Outcomes were ankle dorsiflexion passive range of motion of the affected side, and calf muscle spasticity, measured with the modified Ashworth scale and the Tardieu Scale.

RESULTS

Significant improvements were measured after diagnostic nerve block and botulinum toxin injection compared with the baseline condition. Diagnostic nerve block led to significantly greater improvements in all outcomes than botulinum toxin injection.

CONCLUSION

This study confirmed diagnostic nerve block as a valuable screening tool in deciding whether to treat spastic equinovarus with botulinum toxin. However, the results support the evidence that diagnostic nerve block results in a greater reduction in muscle overactivity than does botulinum toxin type A in patients with spastic equinovarus due to stroke.

摘要

目的

评估诊断性神经阻滞在预测慢性脑卒中后痉挛性马蹄内翻足接受肉毒毒素 A 治疗结果中的作用。

设计

回顾性观察性研究。

患者

50 例慢性脑卒中痉挛性马蹄内翻足患者。

方法

每位患者均行诊断性胫神经阻滞(2%利多卡因周围神经注射)评估,随后在神经阻滞所针对的相同肌肉中注射肉毒毒素 A。所有患者在诊断性神经阻滞前、神经阻滞后及肉毒毒素注射后 4 周进行评估。结果为患侧踝关节背屈被动活动范围,以及小腿肌肉痉挛,用改良 Ashworth 量表和 Tardieu 量表进行测量。

结果

与基线相比,诊断性神经阻滞和肉毒毒素注射后均有显著改善。与肉毒毒素注射相比,诊断性神经阻滞在所有结果上均导致显著更大的改善。

结论

本研究证实诊断性神经阻滞是一种有价值的筛选工具,可用于决定是否使用肉毒毒素治疗痉挛性马蹄内翻足。然而,结果支持以下证据,即在因脑卒中导致痉挛性马蹄内翻足的患者中,与肉毒毒素 A 相比,诊断性神经阻滞可导致肌肉过度活动的更大减少。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验