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[不同因素对实验室小鼠胚胎发育中性别比例的影响]

[Effect of different factors on the sex ratio in laboratory mouse embryogenesis].

作者信息

Udalova L D

出版信息

Arkh Anat Gistol Embriol. 1985 Dec;89(12):28-31.

PMID:3841478
Abstract

Influence of two factors on distribution of embryos according to the sex is considered: genetic peculiarities of inbred mice and hybrid mice, as well as spontaneous embryonal death of the embryos of different sex. The work has been performed on C3H, CBA, C57BL strains of mice and on hybrid mice of CBA/C57BL and ICR/In(X)1H strains. The sex ratio in the mice studied is balanced. In the CBA/C57BL hybrid mice a certain shift in the sex ratio is noted towards female embryos. In the offspring of the ICR/In(X)1H hybrid mice the sex distribution of the embryos does not differ from the ratio 1:1. The results of the investigation confirm the opinion of the literature that genetic peculiarities of the inbred mice do not essentially influence the sex ratio in their offspring, while fluctuation in the sex ratio in the hybrid mice are evidently connected, in a greater degree, with their genetic peculiarities. As demonstrates the analysis of the sex relation and the embryonal death, there is no selective death in the embryos of any sex during embryogenesis in the mice investigated.

摘要

研究了两个因素对胚胎性别分布的影响

近交系小鼠和杂交系小鼠的遗传特性,以及不同性别的胚胎自然胚胎死亡情况。实验选用了C3H、CBA、C57BL品系的小鼠以及CBA/C57BL和ICR/In(X)1H品系的杂交小鼠。所研究小鼠的性别比例是平衡的。在CBA/C57BL杂交小鼠中,性别比例向雌性胚胎有一定偏移。在ICR/In(X)1H杂交小鼠的后代中,胚胎的性别分布与1:1的比例没有差异。研究结果证实了文献中的观点,即近交系小鼠的遗传特性对其后代的性别比例没有实质性影响,而杂交系小鼠性别比例的波动在很大程度上显然与其遗传特性有关。对性别关系和胚胎死亡情况的分析表明,在所研究的小鼠胚胎发育过程中,任何性别的胚胎都没有选择性死亡。

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[Effect of different factors on the sex ratio in laboratory mouse embryogenesis].[不同因素对实验室小鼠胚胎发育中性别比例的影响]
Arkh Anat Gistol Embriol. 1985 Dec;89(12):28-31.
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