Kryshkina V P, Malashenko A M
Genetika. 1975;11(3):68-73.
The object of this investigation was the potential fecundity of four inbred strains of mice, viz. BALB/c, B10.SW, CC57W, A/Sn and of their different hybrid combinations. The inbred strains studied had different normal ovulation numbers varying from 9,2 to 11,9 and different death-rate of embryos before (10,99-39,49%) and after (9,05-22,47%) the implantation. The numbers of live embryos per female in the strains A/Sn, b10.cw and CC57W were practically equal to one another, but significantly larger than in the strain BALB/c. Interlinear crosses resulted in a considerable decrease of the totalembryonic deathrate, while the normal ovulation number did not undergo any changes. The number of liver embryos in simple hybrids did not differ significantly from that in the maternal inbred strains. Therefore the heterozygosity of embryos did not affect significantly the potential fecunidity of females. The number of surviving embryos per female increased in the cross between the simple hybrids (BALB/cXB10.CW) X (CC57WXA/Sn) to 8,9+/-0,37. This heterosis was the result of the total death-rate of embryos down to 14,89%. Asit is shown by the comparison of the potential fecundity of pregnant females carrrying homo- and heterozygous embryos to that of pregnant hybrid females, the rate of survival of embryos depends more on th
本研究的对象是四种近交系小鼠,即BALB/c、B10.SW、CC57W、A/Sn及其不同的杂交组合的潜在繁殖力。所研究的近交系正常排卵数不同,从9.2到11.9不等,胚胎在着床前(10.99%-39.49%)和着床后(9.05%-22.47%)的死亡率也不同。A/Sn、B10.CW和CC57W品系中每只雌性的活胚胎数实际上彼此相等,但显著高于BALB/c品系。品系间杂交导致胚胎总死亡率显著降低,而正常排卵数没有任何变化。简单杂交后代中的活胚胎数与母本近交系中的活胚胎数没有显著差异。因此,胚胎的杂合性对雌性的潜在繁殖力没有显著影响。在简单杂交组合(BALB/c×B10.CW)×(CC57W×A/Sn)的杂交后代中,每只雌性存活胚胎数增加到8.9±0.37。这种杂种优势是胚胎总死亡率降至14.89%的结果。通过比较携带纯合和杂合胚胎的怀孕雌性与怀孕杂交雌性的潜在繁殖力表明,胚胎的存活率更多地取决于……