Yan-Quiroz Edgar Fermín, Agreda-Castro Folker Mijaíl, Diaz-Lozano Lita, Tenazoa-Villalobos Richard, Fernández-Rodríguez Lissett Jeanette
Hospital de Alta Complejidad Virgen de la Puerta - EsSalud, La Esperanza 13013, Perú.
Faculty of Medicine, Universidad Privada Antenor Orrego, Trujillo 13008, Perú.
Ecancermedicalscience. 2023 Oct 5;17:1610. doi: 10.3332/ecancer.2023.1610. eCollection 2023.
Anorectal melanoma is a rare and difficult-to-diagnose highly malignant cancer with a poor prognosis. The treatment usually involves surgery and often includes adjuvants such as radiation therapy and immunotherapy. We present a case of a 77-year-old Peruvian who was eventually diagnosed with this cancer during the COVID-19 pandemic, which complicated her treatment and allowed the cancer to spread. Her treatment included abdominoperineal resection, bilateral pelvic lymphadenectomy, left internal iliac vein raffia and end colostomy, followed by 3D radiation therapy (50 Gy, 25 sessions) and systemic treatment with nivolumab, all of which were well tolerated. The patient was alive as of 20 August 2023, having survived for more than 3 years since the onset of symptoms.
肛管黑色素瘤是一种罕见且难以诊断的高恶性癌症，预后较差。治疗通常包括手术，且常常涉及放疗和免疫疗法等辅助治疗。我们报告一例77岁秘鲁女性病例，她最终在新冠疫情期间被诊断出患有这种癌症，这使她的治疗变得复杂，导致癌症扩散。她的治疗包括腹会阴联合切除术、双侧盆腔淋巴结清扫术、左髂内静脉结扎术和末端结肠造口术，随后进行三维放疗（50 Gy，25次）和纳武单抗全身治疗，所有这些治疗患者耐受性良好。截至2023年8月20日，患者仍然存活，自出现症状以来已存活超过3年。
