Editorial: Platelets in tumor biology: from molecular mechanisms to clinical applications.
作者信息
Aris Mariana, Sood Anil K, Zaslavsky Alexander
机构信息
Centro de Investigaciones Oncológicas-Fundación Cáncer (CIO-FUCA), Buenos Aires, Argentina.
Department of Gynecologic Oncology and Reproductive Medicine, UT MD Anderson Cancer Center, Houston, TX, United States.
出版信息
Front Cell Dev Biol. 2024 Feb 13;12:1373463. doi: 10.3389/fcell.2024.1373463. eCollection 2024.
Abstract
摘要
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本文引用的文献
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Tumour cell-activated platelets modulate the immunological activity of CD4, CD8, and NK cells, which is efficiently antagonized by heparin.肿瘤细胞激活的血小板可调节CD4、CD8和NK细胞的免疫活性，而肝素可有效对抗这种调节作用。
Cancer Immunol Immunother. 2022 Oct;71(10):2523-2533. doi: 10.1007/s00262-022-03186-5. Epub 2022 Mar 14.
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Lessons to learn from tumor-educated platelets.从肿瘤教育的血小板中吸取教训。
Blood. 2021 Jun 10;137(23):3174-3180. doi: 10.1182/blood.2019003976.
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Platelet PD-L1 suppresses anti-cancer immune cell activity in PD-L1 negative tumors.血小板 PD-L1 抑制 PD-L1 阴性肿瘤中的抗肿瘤免疫细胞活性。
Sci Rep. 2020 Nov 9;10(1):19296. doi: 10.1038/s41598-020-76351-4.
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Tumor-educated platelets.肿瘤教育的血小板。
Blood. 2019 May 30;133(22):2359-2364. doi: 10.1182/blood-2018-12-852830. Epub 2019 Mar 4.
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The Platelet Napoleon Complex-Small Cells, but Big Immune Regulatory Functions.血小板拿破仑情结——小细胞，大免疫调节功能。
Annu Rev Immunol. 2019 Apr 26;37:125-144. doi: 10.1146/annurev-immunol-042718-041607. Epub 2018 Nov 28.
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Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications.血小板固有前体 mRNA 在生理刺激激活时发生剪接，导致功能相关的蛋白质组修饰。
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