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[缓慢性心律失常诊断的历史发展：德国临床电生理学的早期岁月]

[Historical development of diagnosis of bradyarrhythmias : The early years of clinical electrophysiology in Germany].

作者信息

Breithardt Günter

机构信息

Universitäres Herzzentrum, Klinik für Kardiologie, Universitätsklinikum Münster, Münster, Deutschland.

出版信息

Herzschrittmacherther Elektrophysiol. 2024 Mar;35(Suppl 1):5-17. doi: 10.1007/s00399-024-01006-0. Epub 2024 Feb 28.

DOI:10.1007/s00399-024-01006-0
PMID:38416158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10923979/
Abstract

The introduction of His bundle electrography by Benjamin Scherlag (New York) in 1969, together with programmed stimulation of the heart by Philip Coumel (Paris) in 1967, and Hein Wellens (Amsterdam) in 1972, were decisive turning points on the way to invasive electrophysiology and the development of an independent, now distinctly interventional subspecialty of cardiology. The main topic of the 1970s was bradycardic arrhythmias, promoted by pacemaker therapy, which had been introduced just over 10 years earlier. The recording of the potentials of the bundle of His and other recording locations in the atria and ventricles allowed a differentiated assessment of the excitation process and the refractory periods. High-rate atrial stimulation to determine sinus node recovery time and premature stimulation to determine sinoatrial conduction time were developed to analyze sinoatrial node function. This article describes the introduction of His bundle electrography in a gradually increasing number of centers in Germany and their scientific contribution.

摘要

1969年，本杰明·舍尔拉格（纽约）引入希氏束电图，1967年菲利普·库梅尔（巴黎）以及1972年海因·韦伦斯（阿姆斯特丹）开展心脏程控刺激，这些都是侵入性电生理学发展道路上的决定性转折点，也是心脏病学一个独立的、如今已颇具特色的介入亚专业得以发展的关键。20世纪70年代的主要课题是心动过缓性心律失常，这受到起搏器治疗的推动，起搏器治疗在10多年前刚刚问世。记录希氏束以及心房和心室其他记录部位的电位，有助于对兴奋过程和不应期进行差异化评估。为分析窦房结功能，人们开发出了用于测定窦房结恢复时间的高频率心房刺激以及用于测定窦房传导时间的期前刺激。本文介绍了希氏束电图在德国越来越多的中心的引入情况及其科学贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c0f/10923979/b29caeb88ca4/399_2024_1006_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c0f/10923979/71e3727c2c54/399_2024_1006_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c0f/10923979/fea921dda44a/399_2024_1006_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c0f/10923979/cfa83b7e1462/399_2024_1006_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c0f/10923979/b29caeb88ca4/399_2024_1006_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c0f/10923979/71e3727c2c54/399_2024_1006_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c0f/10923979/fea921dda44a/399_2024_1006_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c0f/10923979/cfa83b7e1462/399_2024_1006_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c0f/10923979/b29caeb88ca4/399_2024_1006_Fig4_HTML.jpg

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[Historical development of diagnosis of bradyarrhythmias : The early years of clinical electrophysiology in Germany].[缓慢性心律失常诊断的历史发展：德国临床电生理学的早期岁月]
Herzschrittmacherther Elektrophysiol. 2024 Mar;35(Suppl 1):5-17. doi: 10.1007/s00399-024-01006-0. Epub 2024 Feb 28.
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His bundle electrography.希氏束电图描记法
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[Bradyarrhythmias: diagnostics].[缓慢性心律失常：诊断]
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Klin Wochenschr. 1975 Jun 1;53(11):499-507. doi: 10.1007/BF01468754.
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[The effect of ouabain on sinus node function and intracardiac conduction (author's transl)].哇巴因对窦房结功能及心内传导的影响（作者译）
Z Kardiol. 1977 May;66(5):223-30.
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Atrial pacing: intracardiac conduction assessed by his bundle electrograms acquired from the permanent atrial electrode at implantation.心房起搏：通过植入时从永久性心房电极获取的希氏束电图评估心内传导。
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[Analysis of the stimulus formation and excitation conduction systems by electrostimulation and intracardiac registration of the ECG (author's transl)].通过电刺激和心内心电图记录对刺激形成和兴奋传导系统的分析（作者译）
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[State of the heart conduction system in the sick sinus syndrome (according to the recording of the bundle of His potentials and the atrial stimulation test)].[病窦综合征中心脏传导系统的状态（根据希氏束电位记录及心房刺激试验）]
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