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含氟牙膏中锡与牙齿磨损防护相关的特性。

Characteristics of tin-containing fluoride toothpastes related to erosive tooth wear protection.

作者信息

Sakae Letícia Oba, Kairalla Cláudia Allegrini, Viana Ítallo Emídio Lira, Carvalho Thiago Saads, Niemeyer Samira Helena, Hara Anderson Takeo, Scaramucci Taís

机构信息

Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, São Paulo, SP 05508-000, Brazil.

Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, São Paulo, SP 05508-000, Brazil; Department of Comprehensive Care, Division of Operative Dentistry, Tufts University School of Dental Medicine, 1 Kneeland Street, Boston, MA 02111, USA.

出版信息

J Dent. 2024 Apr;143:104901. doi: 10.1016/j.jdent.2024.104901. Epub 2024 Feb 27.

Abstract

OBJECTIVES

To assess the effect of different tin-containing toothpastes on the control of erosive tooth wear in enamel and dentin.

METHODS

Enamel and dentin slabs were randomly distributed into 7 experimental groups (n = 10/substrate): C-: negative control (Artificial saliva); AmF (regular fluoridated toothpaste without tin); Sn-1 (SnF/NaF); Sn-2 (SnF/NaF/SnCl); Sn-3 (SnCl/NaF); Sn-4 (SnF/SnCl); Sn-5 (SnCl/AmF/NaF/chitosan). Specimens were submitted to 5-day erosion-abrasion cycling. Surface loss (SL) was determined with an optical profilometer. Tin deposition on the tooth surfaces and some characteristics of the toothpastes (pH, potentially available F, %weight of solid particles, and RDA) were also assessed. Data were statistically analyzed (α = 0.05).

RESULTS

For enamel, the Sn-2 presented the lowest SL, not differing significantly from AmF, C+, and Sn-3. The SL of these groups was significantly lower than the C-, except for Sn-3. Sn-1 and Sn-4 were also not significantly different from C-. For dentin, C- significantly showed the highest SL values, whilst, Sn-1 presented the lowest SL, not differing significantly from AmF, Sn-2, C+, and Sn-3. There was a significant positive association between enamel SL and the pH and tin deposition. Dentin SL was significantly negatively associated with the %weight of solid particles and RDA.

CONCLUSIONS

Most of the tin-toothpastes were able to exhibit some protection against ETW. In this process, the toothpastes characteristics play a role, as lower enamel SL was significantly associated with lower pH values and tin deposition; and lower dentin SL was associated with higher %weight of solid particles and RDA of the toothpastes.

CLINICAL SIGNIFICANCE

Tin-containing toothpastes can be used for erosive tooth wear protection, but our study showed that their effect depends on the pH, amount of tin deposition, % weight of solid particles and RDA of the toohpastes.

摘要

目的

评估不同含锡牙膏对控制牙釉质和牙本质侵蚀性牙齿磨损的效果。

方法

将牙釉质和牙本质薄片随机分为7个实验组(每种基质n = 10):C-:阴性对照(人工唾液);AmF(不含锡的常规含氟牙膏);Sn-1(SnF/NaF);Sn-2(SnF/NaF/SnCl);Sn-3(SnCl/NaF);Sn-4(SnF/SnCl);Sn-5(SnCl/AmF/NaF/壳聚糖)。将标本进行为期5天的侵蚀-磨损循环。用光学轮廓仪测定表面损失(SL)。还评估了牙齿表面的锡沉积以及牙膏的一些特性(pH值、潜在可用氟、固体颗粒重量百分比和RDA)。对数据进行统计学分析(α = 0.05)。

结果

对于牙釉质,Sn-2的SL最低,与AmF、C+和Sn-3无显著差异。除Sn-3外,这些组的SL显著低于C-。Sn-1和Sn-4与C-也无显著差异。对于牙本质,C-显著显示出最高的SL值,而Sn-1的SL最低,与AmF、Sn-2、C+和Sn-3无显著差异。牙釉质SL与pH值和锡沉积之间存在显著的正相关。牙本质SL与固体颗粒重量百分比和RDA显著负相关。

结论

大多数含锡牙膏能够对侵蚀性牙齿磨损起到一定的保护作用。在此过程中,牙膏的特性发挥了作用,因为较低的牙釉质SL与较低的pH值和锡沉积显著相关;而较低的牙本质SL与牙膏中较高的固体颗粒重量百分比和RDA相关。

临床意义

含锡牙膏可用于保护侵蚀性牙齿磨损,但我们的研究表明,其效果取决于牙膏的pH值、锡沉积量、固体颗粒重量百分比和RDA。

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