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评估“个人化!+”对轻度智力残疾或边缘智力功能障碍合并物质使用障碍人群的有效性:一项多基线单病例实验研究。

Evaluating the Effectiveness of Take it Personal!+ in People With Mild Intellectual Disability or Borderline Intellectual Functioning and Substance Use Disorder: A Multiple Baseline Single-Case Experimental Study.

机构信息

Research and Development, Pluryn, and Behavioural Science Institute.

Research and Development, Pluryn, and Behavioural Science Institute.

出版信息

Behav Ther. 2024 Mar;55(2):331-346. doi: 10.1016/j.beth.2023.07.007. Epub 2023 Jul 25.

DOI:10.1016/j.beth.2023.07.007
PMID:38418044
Abstract

Individuals with mild intellectual disabilities or borderline intellectual functioning are at increased risk to develop a substance use disorder-however, effective treatment programs adapted to this target group are scarce. This study evaluated the effectiveness of Take it Personal!+ in individuals with mild intellectual disabilities or borderline intellectual functioning and substance use disorder. Take it Personal!+ is a personalized treatment based on motivational interviewing and cognitive-behavioral therapy supported by an mHealth application. Data were collected in a nonconcurrent multiple baseline single-case experimental design across individuals with four phases (i.e., baseline, treatment, posttreatment, and follow-up). Twelve participants were randomly allocated to baseline lengths varying between 7 and 11 days. Substance use quantity was assessed during baseline, treatment, and posttreatment with a daily survey using a mobile application. Visual analysis was supported with statistical analysis of the daily surveys by calculating three effect size measures in 10 participants (two participants were excluded from this analysis due to a compliance rate below 50%). Secondary, substance use severity was assessed with standardized questionnaires at baseline, posttreatment, and follow-up and analyzed by calculating the Reliable Change Index. Based on visual analysis of the daily surveys, 10 out of 12 participants showed a decrease in mean substance use quantity from baseline to treatment and, if posttreatment data were available, to posttreatment. Statistical analysis showed an effect of Take it Personal!+ in terms of a decrease in daily substance use in 8 of 10 participants from baseline to treatment and if posttreatment data were available, also to posttreatment. In addition, data of the standardized questionnaires showed a decrease in substance use severity in 8 of 12 participants. These results support the effectiveness of Take it Personal!+ in decreasing substance use in individuals with mild intellectual disabilities or borderline intellectual functioning.

摘要

个体轻度智力障碍或边缘智力功能障碍者发生物质使用障碍的风险增加,然而,针对该目标群体的有效治疗方案却很匮乏。本研究评估了 Take it Personal!+在轻度智力障碍或边缘智力功能障碍且伴有物质使用障碍个体中的疗效。Take it Personal!+是一种个性化治疗方案,基于动机性访谈和认知行为疗法,并通过移动健康应用程序提供支持。数据通过跨个体的四阶段(基线、治疗、治疗后和随访)收集,采用非同期多个基线单病例实验设计。12 名参与者被随机分配到时长为 7 至 11 天的基线期。使用移动应用程序每天进行一次问卷调查,评估物质使用量,在基线期、治疗期和治疗后进行。视觉分析得到了 10 名参与者的每日调查统计分析的支持,计算了三个效应量指标。由于两名参与者的依从率低于 50%,他们被排除在分析之外。次要结果,使用标准化问卷在基线期、治疗后和随访期评估物质使用严重程度,并通过计算可靠变化指数进行分析。基于每日调查的视觉分析,12 名参与者中有 10 名的物质使用量从基线期到治疗期,以及如果有治疗后数据的话,从治疗期到治疗后都呈现下降趋势。统计分析显示,从基线期到治疗期,以及如果有治疗后数据的话,治疗后,Take it Personal!+对 10 名参与者中的 8 名的每日物质使用量有降低作用。此外,标准化问卷的数据显示,12 名参与者中有 8 名的物质使用严重程度降低。这些结果支持 Take it Personal!+在降低轻度智力障碍或边缘智力功能障碍个体的物质使用量方面的有效性。

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