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术前诊断性检查和老年评估在虚弱的机构化老年髋部骨折患者中的价值;FRAIL-HIP 研究的二次分析。

The value of preoperative diagnostic testing and geriatric assessment in frail institutionalized elderly with a hip fracture; a secondary analysis of the FRAIL-HIP study.

机构信息

Trauma Research Unit, Department of Surgery, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

Department of Clinical Geriatrics, Rijnstate Hospital, Arnhem, The Netherlands.

出版信息

Eur Geriatr Med. 2024 Jun;15(3):753-763. doi: 10.1007/s41999-024-00945-8. Epub 2024 Feb 28.

Abstract

PURPOSE

The aim of this study was to provide a comprehensive overview of (preoperative and geriatric) diagnostic testing, abnormal diagnostic tests and their subsequent interventions, and clinical relevance in frail older adults with a hip fracture.

METHODS

Data on clinical consultations, radiological, laboratory, and microbiological diagnostics were extracted from the medical files of all patients included in the FRAIL-HIP study (inclusion criteria: hip fracture, > 70 years, living in a nursing home with malnourishment/cachexia and/or impaired mobility and/or severe co-morbidity). Data were evaluated until hospital discharge in nonoperatively treated patients and until surgery in operatively treated patients.

RESULTS

A total of 172 patients (88 nonoperative and 84 operative) were included, of whom 156 (91%) underwent laboratory diagnostics, 126 (73%) chest X-rays, and 23 (13%) CT-scans. In 153/156 (98%) patients at least one abnormal result was found in laboratory diagnostics. In 82/153 (50%) patients this did not result in any additional diagnostics or (pharmacological) intervention. Abnormal test results were mentioned as one of the deciding arguments for operative delay (> 24 h) for 10/84 (12%) patients and as a factor in the decision between nonoperative and operative treatment in 7/172 (4%) patients.

CONCLUSION

A large number and variety of diagnostics were performed in this patient population. Abnormal test results in laboratory diagnostics were found for almost all patients and, in majority, appear to have no direct clinical consequences. To prevent unnecessary diagnostics, prospective research is required to evaluate the clinical consequences and added value of the separate elements of preoperative diagnostic testing and geriatric assessment in frail hip fracture patients.

摘要

目的

本研究旨在全面概述(术前和老年医学)诊断检测、异常诊断检测及其后续干预措施,以及 frail 老年髋部骨折患者的临床相关性。

方法

从 FRAIL-HIP 研究中纳入的所有患者(纳入标准:髋部骨折,>70 岁,在疗养院居住,存在营养不良/恶病质和/或活动能力受损和/或严重合并症)的医疗档案中提取临床会诊、影像学、实验室和微生物学诊断的数据。在非手术治疗患者中,数据评估直至出院,在手术治疗患者中,数据评估直至手术。

结果

共纳入 172 例患者(88 例非手术治疗和 84 例手术治疗),其中 156 例(91%)进行了实验室诊断,126 例(73%)进行了胸部 X 光检查,23 例(13%)进行了 CT 扫描。在 153/156 例(98%)患者中,实验室诊断至少有一项异常结果。在 82/153 例(50%)患者中,这并未导致任何额外的诊断或(药物)干预。10/84 例(12%)患者因异常检查结果而延迟手术(>24 小时),7/172 例(4%)患者将异常检查结果作为非手术和手术治疗之间的决策因素之一。

结论

在该患者人群中进行了大量且多样化的诊断。在实验室诊断中发现几乎所有患者都有异常检查结果,且大多数情况下,这些异常结果似乎没有直接的临床后果。为了防止不必要的诊断,需要进行前瞻性研究来评估 frail 髋部骨折患者术前诊断检测和老年评估的各个元素的临床后果和附加价值。

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