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老年骨科评估参数对死亡率的预后价值:一项为期2年的随访研究。

Prognostic value of orthogeriatric assessment parameters on mortality: a 2-year follow-up.

作者信息

Wiedl Andreas, Förch Stefan, Fenwick Annabel, Mayr Edgar

机构信息

Universitätsklinikum Augsburg, Abteilung Für Unfallchirurgie, Orthopädie, Plastische und Handchirurgie, Stenglinstraße 2, 86156, Augsburg, Germany.

出版信息

Eur J Trauma Emerg Surg. 2022 Aug;48(4):2905-2914. doi: 10.1007/s00068-021-01727-8. Epub 2021 Jun 25.

Abstract

INTRODUCTION

Since the arise of orthogeriatric co-management patients' outcome and survival has improved. There are several assessment parameters that screen the precondition of orthogeriatric patients including mobility, activities of daily living, comorbidities, place of residence and need for care just to name a few. In a 2-year follow-up on an orthogeriatric co-managed ward the fracture-independent predictive value of typical assessment parameters and comorbidities on the associated mortality was examined.

METHODS

All patients treated on an orthogeriatric co-managed ward from February 2014 to January 2015 were included. No fracture entity was preferred. Emphasis was set on following parameters: age, gender, Parker-Mobility Score (PMS), Barthel Index (BI), Charlson-Comorbidity Index (CCI), dementia, depression, sarcopenia, frequent falling, length of stay (LOS), care level (CL) and place of residence (POR). In a 2-year follow-up the patients' death rates were acquired. SPSS (IBM Corp., Armonk, New York, USA) and Cox regression was used to univariately analyze the expression of the mentioned parameters and mortality course over 2 years from discharge. In a multivariate analysis intercorrelations and independent relationships were examined.

RESULTS

A follow-up rate of 79.6% by assessing 661 patients was achieved. In the univariate analysis linear inverse correlation between PMS and BI and mortality and a linear positive correlation between CCI and higher mortality were observed. There was also a significant relationship between lower survival and age, dementia, sarcopenia, frequent falling, higher institutionalized place of residence and higher CL. No univariate correlation between 2-year mortality and gender, depression and LOS was found. In the multivariate Cox regression, the only independent risk factors remaining were lower PMS (HR: 1.81; 95%CI: 1.373-2.397), lower BI (HR: 1.64; 95%CI: 1.180-2.290) and higher age per year (HR: 1.04; 95%CI: 1.004-1.067).

CONCLUSION

Age, PMS, BI, CCI, preexisting dementia, sarcopenia, frequent falling, POR and CL are univariate predictors of survival in the orthogeriatric context. An independency could only be found for PMS, BI and age in our multivariate model. This underlines the importance of preexisting mobility and capability of self-support for the patient's outcome in terms of survival.

摘要

引言

自从老年骨科联合管理出现以来,患者的治疗效果和生存率有所提高。有几个评估参数可用于筛查老年骨科患者的术前状况,包括活动能力、日常生活活动能力、合并症、居住地点和护理需求等等。在一个老年骨科联合管理病房进行的为期2年的随访中,研究了典型评估参数和合并症对相关死亡率的骨折无关预测价值。

方法

纳入2014年2月至2015年1月在老年骨科联合管理病房接受治疗的所有患者。不偏袒任何骨折类型。重点关注以下参数:年龄、性别、帕克活动能力评分(PMS)、巴氏指数(BI)、查尔森合并症指数(CCI)、痴呆、抑郁、肌肉减少症、频繁跌倒、住院时间(LOS)、护理级别(CL)和居住地点(POR)。在为期2年的随访中,获取患者的死亡率。使用SPSS(美国纽约州阿蒙克市IBM公司)和Cox回归对上述参数的表达以及出院后2年的死亡率进行单因素分析。在多因素分析中,研究相互关系和独立关系。

结果

通过评估661名患者,随访率达到79.6%。在单因素分析中,观察到PMS与BI和死亡率之间呈线性负相关,CCI与较高死亡率之间呈线性正相关。较低的生存率与年龄、痴呆、肌肉减少症、频繁跌倒、较高的机构化居住地点和较高的CL之间也存在显著关系。未发现2年死亡率与性别、抑郁和住院时间之间存在单因素相关性。在多因素Cox回归中,仅剩下的独立危险因素是较低的PMS(HR:1.81;95%CI:1.373 - 2.397)、较低的BI(HR:1.64;95%CI:1.180 - 2.290)和每年较高的年龄(HR:1.04;95%CI:1.004 - 1.067)。

结论

在老年骨科背景下,年龄、PMS、BI、CCI、既往痴呆、肌肉减少症、频繁跌倒、POR和CL是生存的单因素预测指标。在我们的多因素模型中,仅发现PMS、BI和年龄具有独立性。这强调了患者生存结局方面,既往活动能力和自我支持能力的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97c0/9360057/598595053f31/68_2021_1727_Fig1_HTML.jpg

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